Detection of immunogenic cell death and its relevance for cancer therapy

J Fucikova, O Kepp, L Kasikova, G Petroni… - Cell death & …, 2020 - nature.com
Chemotherapy, radiation therapy, as well as targeted anticancer agents can induce clinically
relevant tumor-targeting immune responses, which critically rely on the antigenicity of …

Antitumour dendritic cell vaccination in a priming and boosting approach

A Harari, M Graciotti, M Bassani-Sternberg… - Nature Reviews Drug …, 2020 - nature.com
Mobilizing antitumour immunity through vaccination potentially constitutes a powerful
anticancer strategy but has not yet provided robust clinical benefits in large patient …

Cancer vaccines as promising immuno-therapeutics: platforms and current progress

J Liu, M Fu, M Wang, D Wan, Y Wei, X Wei - Journal of Hematology & …, 2022 - Springer
Research on tumor immunotherapy has made tremendous progress in the past decades,
with numerous studies entering the clinical evaluation. The cancer vaccine is considered a …

Recent advances and challenges in cancer immunotherapy

C Peterson, N Denlinger, Y Yang - Cancers, 2022 - mdpi.com
Simple Summary Immunotherapy helps a person's immune system to target tumor cells.
Recent advances in cancer immunotherapy, including immune checkpoint inhibition …

Induction of tolerance and immunity by dendritic cells: mechanisms and clinical applications

J Fucikova, L Palova-Jelinkova, J Bartunkova… - Frontiers in …, 2019 - frontiersin.org
Dendritic cells (DCs) are key regulators of immune responses that operate at the interface
between innate and adaptive immunity, and defects in DC functions contribute to the …

Trial watch: dendritic cell vaccination for cancer immunotherapy

J Sprooten, J Ceusters, A Coosemans… - …, 2019 - Taylor & Francis
Dendritic-cells (DCs) have received considerable attention as potential targets for the
development of anticancer vaccines. DC-based anticancer vaccination relies on patient …

Dendritic cells as orchestrators of anticancer immunity and immunotherapy

I Heras-Murillo, I Adán-Barrientos, M Galán… - Nature Reviews …, 2024 - nature.com
Dendritic cells (DCs) are a heterogeneous group of antigen-presenting innate immune cells
that regulate adaptive immunity, including against cancer. Therefore, understanding the …

Biomarkers of radiotherapy-induced immunogenic cell death

RDW Vaes, LEL Hendriks, M Vooijs, D De Ruysscher - Cells, 2021 - mdpi.com
Radiation therapy (RT) can induce an immunogenic variant of regulated cell death that can
initiate clinically relevant tumor-targeting immune responses. Immunogenic cell death (ICD) …

[HTML][HTML] Dendritic cells and immunogenic cancer cell death: a combination for improving antitumor immunity

MJ Lamberti, A Nigro, FM Mentucci, NB Rumie Vittar… - Pharmaceutics, 2020 - mdpi.com
The safety and feasibility of dendritic cell (DC)-based immunotherapies in cancer
management have been well documented after more than twenty-five years of …

Dendritic cell vaccines in ovarian cancer

X Zhang, T He, Y Li, L Chen, H Liu, Y Wu… - Frontiers in …, 2021 - frontiersin.org
Ovarian cancer (OC) is one of the most lethal malignant gynecologic tumors, characterized
by an uncertain presentation and poor outcomes. With or without neoadjuvant …