Taar1-mediated modulation of presynaptic dopaminergic neurotransmission: role of D2 dopamine autoreceptors
Abstract Trace Amine-Associated Receptor 1 (TAAR1) is a G protein-coupled receptor
(GPCR) expressed in several mammalian brain areas and activated by “trace amines”(TAs) …
(GPCR) expressed in several mammalian brain areas and activated by “trace amines”(TAs) …
Ceftriaxone normalizes nucleus accumbens synaptic transmission, glutamate transport, and export following cocaine self-administration and extinction training
H Trantham-Davidson, RT LaLumiere… - Journal of …, 2012 - Soc Neuroscience
Decreased basal glutamate levels are observed in the rat nucleus accumbens (NA) core
following cocaine self-administration. This disruption of glutamate homeostasis arises from a …
following cocaine self-administration. This disruption of glutamate homeostasis arises from a …
Microfabricated, amperometric, enzyme-based biosensors for in vivo applications
Miniaturized electrochemical in vivo biosensors allow the measurement of fast extracellular
dynamics of neurotransmitter and energy metabolism directly in the tissue. Enzyme-based …
dynamics of neurotransmitter and energy metabolism directly in the tissue. Enzyme-based …
[HTML][HTML] Deep brain stimulation for addictive disorders—where are we now?
In the face of a global epidemic of drug addiction, neglecting to develop new effective
therapies will perpetuate the staggering human and economic costs of substance use. This …
therapies will perpetuate the staggering human and economic costs of substance use. This …
Plug-and-play fiber-optic sensors based on engineered cells for neurochemical monitoring at high specificity in freely moving animals
In vivo detection of neurochemicals, including neurotransmitters and neuromodulators, is
critical for both understanding brain mechanisms and diagnosing brain diseases. However …
critical for both understanding brain mechanisms and diagnosing brain diseases. However …
Within-mice comparison of microdialysis and fiber photometry-recorded dopamine biosensor during amphetamine response
A fundamental concept in neuroscience is the transmission of information between neurons
via neurotransmitters,-modulators, and-peptides. For the past decades, the gold standard for …
via neurotransmitters,-modulators, and-peptides. For the past decades, the gold standard for …
Synergistic attenuation of chronic pain using mu opioid and cannabinoid receptor 2 agonists
SA Grenald, MA Young, Y Wang, MH Ossipov… - …, 2017 - Elsevier
The misuse of prescription opiates is on the rise with combination therapies (eg
acetaminophen or NSAIDs) resulting in severe liver and kidney damage. In recent years …
acetaminophen or NSAIDs) resulting in severe liver and kidney damage. In recent years …
Driven to decay: excitability and synaptic abnormalities in amyotrophic lateral sclerosis
MJ Fogarty - Brain research bulletin, 2018 - Elsevier
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron (MN) disease and is
clinically characterised by the death of corticospinal motor neurons (CSMNs), spinal and …
clinically characterised by the death of corticospinal motor neurons (CSMNs), spinal and …
LC/MS/MS analysis of the endogenous dimethyltryptamine hallucinogens, their precursors, and major metabolites in rat pineal gland microdialysate
SA Barker, J Borjigin, I Lomnicka… - Biomedical …, 2013 - Wiley Online Library
We report a qualitative liquid chromatography–tandem mass spectrometry (LC/MS/MS)
method for the simultaneous analysis of the three known N, N‐dimethyltryptamine …
method for the simultaneous analysis of the three known N, N‐dimethyltryptamine …
Evaluation of electrochemical methods for tonic dopamine detection in vivo
AE Rusheen, TA Gee, DP Jang, CD Blaha… - TrAC Trends in …, 2020 - Elsevier
Dysfunction in dopaminergic neuronal systems underlie a number of neurologic and
psychiatric disorders such as Parkinson's disease, drug addiction, and schizophrenia …
psychiatric disorders such as Parkinson's disease, drug addiction, and schizophrenia …