[HTML][HTML] Recent research progress: Discovery of anti-plant virus agents based on natural scaffold

J Chen, X Luo, Y Chen, Y Wang, J Peng… - Frontiers in …, 2022 - frontiersin.org
Plant virus diseases, also known as “plant cancers”, cause serious harm to the agriculture of
the world and huge economic losses every year. Antiviral agents are one of the most …

Eukaryotic splicing machinery in the plant–virus battleground

CF Su, D Das, M Muhammad Aslam… - Wiley …, 2023 - Wiley Online Library
Plant virual infections are mainly caused by plant‐virus parasitism which affects ecological
communities. Some viruses are highly pathogen specific that can infect only specific plants …

[HTML][HTML] Design, synthesis and biological activity of novel chalcone derivatives containing indole

D Hu, N Zhang, Y Zhang, C Yuan, C Gong… - Arabian Journal of …, 2023 - Elsevier
In this study, 24 chalcone derivatives containing indole were designed and synthesized.
Some of the target compounds exhibited significant antiviral and antibacterial effects. The …

Anti‐TMV activity and mode of action of three alkaloids isolated from Chelidonium majus

W Guo, X Lu, B Liu, H Yan, J Feng - Pest Management Science, 2021 - Wiley Online Library
BACKGROUND Plant viral diseases are difficult to control and have caused serious damage
to the agricultural industry. Recently, botanical biopesticides characterized by environment …

Natural phytoalexin stilbene compound resveratrol and its derivatives as anti-tobacco mosaic virus and anti-phytopathogenic fungus agents

P Song, X Yu, W Yang, Q Wang - Scientific Reports, 2021 - nature.com
Plant diseases caused by plant viruses and pathogens seriously affect crop yield and
quality, and it is very difficult to control them. The discovery of new leads based on natural …

Recent progress of bioactivities, mechanisms of action, total synthesis, structural modifications and structure-activity relationships of indole derivatives: a review

T Li, H Xu - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
Indole (2, 3-benzopyrrole) containing a pyrrolyl ring possesses the characteristic of electron-
rich aromatic compounds. Indole occurs in the oil of jasmine and cloves and coal tar …

Splicing Indoles and 4,5-Dihydro-1H-pyrazoline Structure Gave Birth to Novel Antiviral Agents: Design, Synthesis, and Mechanism Study

L Bai, C Wei, Z Shen, H He, X Yang, S Shi… - Journal of Agricultural …, 2023 - ACS Publications
The specific conation of our research is to invent a series of indole derivatives containing a
4, 5-dihydro-1 H-pyrazoline motif with effective antiviral activity. The anti-potato virus Y (PVY) …

Toad alkaloid for pesticide discovery: Dehydrobufotenine derivatives as novel agents against plant virus and fungi

Z Tian, A Liao, J Kang, Y Gao, A Lu… - Journal of agricultural …, 2021 - ACS Publications
Plant viruses and fungi are a serious threat to food security and natural ecosystems. The
efficient and environment-friendly control methods are urgently needed to help safeguard …

[HTML][HTML] Discovery of novel α-aminophosphonates with hydrazone as potential antiviral agents combined with active fragment and molecular docking

J Tian, R Ji, H Wang, S Li, G Zhang - Frontiers in Chemistry, 2022 - frontiersin.org
A series of novel α-aminophosphonate derivatives containing an acetyl hydrazine moiety
were designed and synthesized based active fragment. Bioassay results demonstrated that …

Hydrazone derivatives in agrochemical discovery and development

Y Wang, S Guo, L Yu, W Zhang, Z Wang, YR Chi… - Chinese Chemical …, 2024 - Elsevier
As a common active substructure, hydrazone has attracted increasing attention and is
considered essential for pesticide discovery. It has been widely regarded as a potential …