DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

Gut-brain axis is a dynamic, complex, and bidirectional communication network between the
gut and brain. Changes in the microbiota-gut-brain axis are responsible for developing …

Choline dietary intake varies such that many people do not achieve adequate intakes. Diet
intake of choline can modulate methylation because, via betaine homocysteine …

The mammalian gastrointestinal tract harbors trillions of commensal microorganisms,
collectively known as the microbiota. The microbiota is a critical source of environmental …

Metabolic diseases are becoming an alarming health issue due to elevated incidences of
these diseases over the past few decades. Various environmental factors are associated …

In the next 10 years, one billion people are estimated to suffer from disabling consequences
of metabolic disorders, making them the number one noncommunicable disease on a global …

Purpose Inconsistent findings have been reported of a link between the use of one-carbon
metabolism–related B vitamins and lung cancer risk. Because of the high prevalence of …

Mediterranean diet has been proposed to promote healthy aging, but its effects on aging
biomarkers have been poorly investigated. We evaluated the impact of a 1-year …

Scope Alterations in DNA methylation patterns are correlated with aging, environmental
exposures, and disease pathophysiology; the possibility of reverting or preventing these …

Both life span and health span are influenced by genetic, environmental and lifestyle factors.
With the genetic influence on human life span estimated to be about 20–25%, epigenetic …