Caring for individuals with a difference of sex development (DSD): a consensus statement

M Cools, A Nordenström, R Robeva, J Hall… - Nature Reviews …, 2018 - nature.com
The term differences of sex development (DSDs; also known as disorders of sex
development) refers to a heterogeneous group of congenital conditions affecting human sex …

Selective androgen receptor modulators: current knowledge and clinical applications

ZJ Solomon, JR Mirabal, DJ Mazur… - Sexual medicine …, 2019 - academic.oup.com
Introduction Selective androgen receptor modulators (SARMs) differentially bind to
androgen receptors depending on each SARM's chemical structure. As a result, SARMs …

Benefits of sexual activity on psychological, relational, and sexual health during the COVID-19 breakout

D Mollaioli, A Sansone, G Ciocca… - The journal of sexual …, 2021 - academic.oup.com
Background The COVID-19–related lockdown has profoundly changed human behaviors
and habits, impairing general and psychological well-being. Along with psychosocial …

[HTML][HTML] Selective androgen receptor modulators: the future of androgen therapy?

AR Christiansen, LI Lipshultz, JM Hotaling… - Translational …, 2020 - ncbi.nlm.nih.gov
Selective androgen receptor modulators (SARMs) are small molecule drugs that function as
either androgen receptor (AR) agonists or antagonists. Variability in AR regulatory proteins …

Interplay between hippocampal TACR3 and systemic testosterone in regulating anxiety-associated synaptic plasticity

MN Wojtas, M Diaz-González, N Stavtseva… - Molecular …, 2023 - nature.com
Abstract Tachykinin receptor 3 (TACR3) is a member of the tachykinin receptor family and
falls within the rhodopsin subfamily. As a G protein-coupled receptor, it responds to …

The molecular mechanisms of sexual orientation and gender identity

AD Fisher, J Ristori, G Morelli, M Maggi - Molecular and cellular …, 2018 - Elsevier
Differences between males and females are widely represented in nature. There are gender
differences in phenotypes, personality traits, behaviors and interests, cognitive performance …

People smoke for nicotine, but lose sexual and reproductive health for tar: a narrative review on the effect of cigarette smoking on male sexuality and reproduction

G Corona, A Sansone, F Pallotti, A Ferlin… - Journal of …, 2020 - Springer
Purpose To systematically review the impact of smoking habits on cardiovascular (CV) as
well as on male sexual and reproductive function and to provide updated evidence on the …

[HTML][HTML] Testosterone deficiency and risk of cognitive disorders in aging males

G Corona, F Guaraldi, G Rastrelli… - The World Journal of …, 2021 - ncbi.nlm.nih.gov
Cognitive impairment and dementia are predicted to undergo a dramatic increase in the
following years with more than 131.5 million people being affected by 2030. Although …

Downregulation of leptin receptor and kisspeptin/GPR54 in the murine hypothalamus contributes to male hypogonadism caused by high-fat diet-induced obesity

L Zhai, J Zhao, Y Zhu, Q Liu, W Niu, C Liu, Y Wang - Endocrine, 2018 - Springer
Purpose Obesity may lead to male hypogonadism, the underlying mechanism of which
remains unclear. In the present study, we established a murine model of male …

Couplepause: deconstructing sick menopause and andropause during midlife

S Rozenberg, RE Nappi, K Schaudig… - The journal of sexual …, 2023 - academic.oup.com
More than 447 million people live today in Europe (48% men and 52% women); of them,
one-fifth (93 million) is between 50 and 64 years of age. It can be inferred that half of them …