Preclinical and human vaccine studies indicate that, although neonatal immunisation does
not generally lead to rapid and strong antibody responses, it may result in an efficient …

Saponins are chemically a heterogeneous group of sterol glycosides and triterpene
glycosides which are common constituents of plants. One source of triterpenoid saponins …

Lassa virus (LASV) is recognized by the World Health Organization as one of the top five
pathogens likely to cause a severe outbreak. A recent unprecedented resurgence of LASV …

Background: Patients with immune-mediated diseases on immunosuppressive therapies
have more infectious episodes than healthy individuals, yet vaccination practices by …

A live-attenuated, intranasal respiratory syncytial virus (RSV) candidate vaccine, cpts-
248/404, was tested in phase 1 trials in 114 children, including 37 1–2-month-old infants—a …

Measles virus (MV) is hypothesized to enter the host by infecting epithelial cells of the
respiratory tract, followed by viremia mediated by infected monocytes. However, neither of …

Aluminum salts are currently the only widely used adjuvant for human vaccines. Over the
past 10–15 years, a large research effort has attempted to find novel adjuvants with ability to …

Immunizing infants against measles at the youngest age possible has the potential to reduce
morbidity and mortality. The ability of infants at 6, 9, or 12 months to respond to measles and …

Live-attenuated vaccines (LAVs) have achieved remarkable successes in controlling virus
spread, as well as for other applications such as cancer immunotherapy. However, with …

This paper reviews literature on passively transferred maternal antibodies against measles
in infants. The amount and decay of these antibodies can be a result of changing patterns in …