Breast cancer: current molecular therapeutic targets and new players

S Nagini - Anti-Cancer Agents in Medicinal Chemistry …, 2017 - ingentaconnect.com
Breast cancer is the most common cancer and the most frequent cause of cancer death
among women worldwide. Breast cancer is a complex, heterogeneous disease classified …

Strategies to reverse hypoxic tumor microenvironment for enhanced sonodynamic therapy

J Li, Z Yue, M Tang, W Wang, Y Sun… - Advanced Healthcare …, 2024 - Wiley Online Library
Sonodynamic therapy (SDT) has emerged as a highly effective modality for the treatment of
malignant tumors owing to its powerful penetration ability, noninvasiveness, site‐confined …

Crosstalk between estrogen signaling and breast cancer metabolism

E Kulkoyluoglu-Cotul, A Arca… - Trends in Endocrinology & …, 2019 - cell.com
Estrogens and estrogen receptors (ERs) regulate metabolism in both normal physiology and
in disease. The metabolic characteristics of intrinsic breast cancer subtypes change based …

Natural products with anti-aging potential: Affected targets and molecular mechanisms

CS Cătană, AG Atanasov, I Berindan-Neagoe - Biotechnology advances, 2018 - Elsevier
In recent years, there has been a great deal of attention toward the molecular machinery
relevant to age-related progression controlled through the external intervention of …

Anacardium Occidentale L. Leaf Extracts Protect Against Glutamate/H2O2-Induced Oxidative Toxicity and Induce Neurite Outgrowth: The Involvement of SIRT1/Nrf2 …

C Duangjan, P Rangsinth, S Zhang, M Wink… - Frontiers in …, 2021 - frontiersin.org
Neurodegenerative diseases are linked to neuronal cell death and neurite outgrowth
impairment that are often caused by oxidative stress. Natural products, which have …

[HTML][HTML] Pivotal role of human stearoyl-CoA desaturases (SCD1 and 5) in breast cancer progression: oleic acid-based effect of SCD1 on cell migration and a novel pro …

C Angelucci, A D'Alessio, F Iacopino, G Proietti… - Oncotarget, 2018 - ncbi.nlm.nih.gov
The influence of cell membrane fluidity on cancer progression has been established in
different solid tumors. We previously reported that “cancer-associated fibroblasts”(CAFs) …

Identification and roles of miR-29b-1-3p and miR29a-3p-regulated and non-regulated lncRNAs in endocrine-sensitive and resistant breast cancer cells

P Muluhngwi, CM Klinge - Cancers, 2021 - mdpi.com
Simple Summary Estrogen receptor α (ERα) is a key driver and clinical target in breast
cancer, with~ 75% of women having ERα+ breast tumors at diagnosis. Endocrine therapies …

Viability of HepG2 and MCF-7 cells is not correlated with mitochondrial bioenergetics

J Doczi, N Karnok, D Bui, V Azarov, G Pallag… - Scientific Reports, 2023 - nature.com
Alterations in metabolism are a hallmark of cancer. It is unclear if oxidative phosphorylation
(OXPHOS) is necessary for tumour cell survival. In this study, we investigated the effects of …

Transcriptomic response of breast cancer cells to anacardic acid

DJ Schultz, A Krishna, SL Vittitow, N Alizadeh-Rad… - Scientific reports, 2018 - nature.com
Anacardic acid (AnAc), a potential dietary agent for preventing and treating breast cancer,
inhibited the proliferation of estrogen receptor α (ERα) positive MCF-7 and MDA-MB-231 …

Interkingdom Hormonal Regulations between Plants and Animals Provide New Insight into Food Safety

H Cheng, W Wang, W Wang, M Yang… - Journal of Agricultural …, 2023 - ACS Publications
Food safety has become an attractive topic among consumers. Raw material production for
food is also a focus of social attention. As hormones are widely used in agriculture and …