Synthesis and in vitro biological evaluation of thiosulfinate derivatives for the treatment of human multidrug-resistant breast cancer

A Roseblade, A Ung, M Bebawy - Acta Pharmacologica Sinica, 2017 - nature.com
Organosulfur compounds derived from Allium vegetables have long been recognized for
various therapeutic effects, including anticancer activity. Allicin, one of the main biologically …

Synergistic anti-cancer action of salicylic acid and cisplatin on HeLa cells elucidated by network pharmacology and in vitro analysis

H Sidhu, N Capalash - Life Sciences, 2021 - Elsevier
Aim To investigate the anti-cancer potential of salicylic acid and cisplatin combination in
HeLa cells and the underlying mechanism. Main methods Drugs and disease targets were …

Genome-wide miRNA response to anacardic acid in breast cancer cells

DJ Schultz, P Muluhngwi, N Alizadeh-Rad, MA Green… - PloS one, 2017 - journals.plos.org
MicroRNAs are biomarkers and potential therapeutic targets for breast cancer. Anacardic
acid (AnAc) is a dietary phenolic lipid that inhibits both MCF-7 estrogen receptor α (ERα) …

Anacardic acid mitigates liver fat accumulation and impaired glucose tolerance in mice fed a high‐fat and high‐sucrose diet

S Chung, EJ Shin, HK Choi, JH Park… - Food science & …, 2020 - Wiley Online Library
In this study, we evaluated the effects of anacardic acid (AA), a phenolic lipid found in
cashew nuts (Anacardium occidentale), on metabolic disorders related to obesity, fatty liver …

[HTML][HTML] Nanoemulsions to support ex vivo cell culture of breast cancer circulating tumor cells

N Carmona-Ule, C Abuín-Redondo, C Costa… - Materials Today …, 2020 - Elsevier
The culture and expansion of circulating tumor cells (CTCs) for ex vivo assays plays an
important role in precision medicine. However, it still represents a big challenge in …

Mitochondria-targeted triphenylphosphonium-based compounds do not affect estrogen receptor α

LA Zinovkina, AK Galivondzhyan, AS Prikhodko… - PeerJ, 2020 - peerj.com
Background Targeting negatively charged mitochondria is often achieved using
triphenylphosphonium (TPP) cations. These cationic vehicles may possess biological …

Regulation of Noncoding RNA by Nutraceuticals: Implication in Neurological Disorders and Cancer

A Balakrishnan, AR Jayakumar, BT Sebastian… - … for Alzheimer's Disease …, 2023 - Springer
Abstract Noncoding RNAs (ncRNAs) are RNAs transcribed from genes but are not
translated. The ncRNAs such as lncRNAs and miRNAs play an important role in the …

Purified anacardic acids exert multiple neuroprotective effects in pesticide model of Parkinson's disease: in vivo and in silico analysis

RL Augusto, IP Mendonça… - IUBMB …, 2020 - Wiley Online Library
Parkinson's disease (PD) induced by environmental toxins involves a multifactorial cascade
of harmful factors, thus motivating the search for therapeutic agents able to act on the …

[图书][B] Nutraceuticals for Alzheimer's Disease: A Promising Therapeutic Approach

AJ Thenmozhi, T Manivasagam - 2023 - Springer
There is clear evidence that a diet rich in specific nutritional food groups (fruits, fish,
vegetables) can reduce the incidence and prevalence of some of the primary clinical …

Herbal Medicinal Compounds and Their Anti–Breast Cancer Actions: A Mechanistic Perspective

DA Gideon, P Annadurai, A Parashar… - … and Biotechnology of …, 2022 - taylorfrancis.com
Next to cardiovascular disease, cancer remains the second leading cause of mortality and
morbidity in the world. Breast cancer is the leading cancer type in women. The high rates of …