Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

Intervertebral disc degeneration (IDD) is a common clinical degenerative disease of the
spine. A series of factors, such as inflammation, oxidative stress and mechanical stress …

Rheumatoid arthritis (RA) is characterized by systemic synovitis leading to joint destruction
in which imbalances in pro-inflammatory and anti-inflammatory cytokines promote the …

Growth plate cartilage has limited self-repair ability, leading to poor bone bridge formation
post-injury and ultimately limb growth defects in children. The current corrective surgeries …

Osteoarthritis (OA), characterized by chondrocyte apoptosis and disturbance of the balance
between catabolism and anabolism of the extracellular matrix (ECM), is the most common …

Rheumatoid arthritis (RA) is a chronic inflammatory disease that eventually leads to
disability. Inflammatory cell infiltration, severe joint breaking and systemic bone loss are the …

Hitchhiking, a recently developed bio-inspired cargo delivery system, has been harnessed
for diverse applications. By leveraging the interactions between nanoparticles and …

Dysfunction of mRNA or RNA-binding proteins (RBPs) causes cellular aging and age-
related degenerative diseases; however, information regarding the mechanism through …

In this review, we have focused mainly on the study of their antioxidant and pro-oxidant
capacity, and the analysis of the oxidation of the catechol group to o-quinone. The redox …

MyoD, Myf5, myogenin, and MRF4 (also known as Myf6 or herculin) are myogenic
regulatory factors (MRFs). MRFs are regarded as master transcription factors that are …