MicroRNAs as active players in the pathogenesis of multiple sclerosis

C Fenoglio, E Ridolfi, D Galimberti… - International journal of …, 2012 - mdpi.com
MicroRNAs (miRNAs) are a recently discovered group of small noncoding RNAs that
regulate gene expression post-transcriptionally. They are highly expressed in cells of the …

The role of microRNAs involved in the disorder of blood–brain barrier in the pathogenesis of multiple sclerosis

A Emami Nejad, SM Mostafavi Zadeh… - Frontiers in …, 2023 - frontiersin.org
miRNAs are involved in various vital processes, including cell growth, development,
apoptosis, cellular differentiation, and pathological cellular activities. Circulating miRNAs …

Administration of a microRNA-21 inhibitor improves the lupus-like phenotype in MRL/lpr mice by repressing Tfh cell-mediated autoimmune responses

X Gao, Y Song, P Du, S Yang, H Cui, S Lu, L Hu… - International …, 2022 - Elsevier
Abstract Background Inhibiting Tfh cell overexpansion prevents autoimmune responses and
disease flares in systemic lupus erythematosus (SLE). miR-21 is highly expressed in SLE …

A MicroRNA signature for evaluation of risk and severity of autoimmune thyroid diseases

R Martínez-Hernández… - The Journal of …, 2018 - academic.oup.com
Abstract Context Circulating microRNAs (miRNAs) are emerging as an interesting research
area because of their potential role as novel biomarkers and therapeutic targets. Their …

MicroRNAs: novel regulators of oligodendrocyte differentiation and potential therapeutic targets in demyelination-related diseases

JS Li, ZX Yao - Molecular neurobiology, 2012 - Springer
MicroRNAs (miRNAs or miRs) are a class of endogenous small non-coding RNAs that
consist of about 22 nucleotides and play critical roles in various biological processes …

The microRNA centrism in the orchestration of neuroinflammation in neurodegenerative diseases

N Nuzziello, M Liguori - Cells, 2019 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs with a unique ability to regulate the
transcriptomic profile by binding to complementary regulatory RNA sequences. The ability of …

Disruption of global hypothalamic microRNA (miR) profiles and associated behavioral changes in California mice (Peromyscus californicus) developmentally exposed …

S Kaur, JA Kinkade, MT Green, RE Martin… - Hormones and …, 2021 - Elsevier
Developmental exposure to endocrine disrupting chemicals (EDCs), eg, bisphenol A (BPA)
or genistein (GEN), causes longstanding epigenome effects. MicroRNAs (miRs) regulate …

Association between the three functional miR-146a single-nucleotide polymorphisms, rs2910164, rs57095329, and rs2431697, and autoimmune disease …

R Park, WJ Lee, JD Ji - Autoimmunity, 2016 - Taylor & Francis
Studies suggest associations between the miR-146a single nucleotide polymorphisms
(SNPs) and susceptibility to autoimmune diseases. However, the results are inconsistent …

A comprehensive review of non-coding RNAs functions in multiple sclerosis

S Ghafouri-Fard, M Taheri - European Journal of Pharmacology, 2020 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system which
affects young individuals and is associated with high morbidity. The extensive burden of this …

Efficient roles of miR-146a in cellular and molecular mechanisms of neuroinflammatory disorders: an effectual review in neuroimmunology

M Aslani, SS Mortazavi-Jahromi, A Mirshafiey - Immunology Letters, 2021 - Elsevier
Known as one of the most sophisticated systems of the human body, the nervous system
consists of neural cells and controls all parts of the body. It is closely related to the immune …