Material design for lymph node drug delivery
A significant fraction of the total immune cells in the body are located in several hundred
lymph nodes, in which lymphocyte accumulation, activation and proliferation are organized …
lymph nodes, in which lymphocyte accumulation, activation and proliferation are organized …
From sewer to saviour—targeting the lymphatic system to promote drug exposure and activity
The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …
Chemistry, biology, and medicine of fluorescent nanomaterials and related systems: new insights into biosensing, bioimaging, genomics, diagnostics, and therapy
J Yao, M Yang, Y Duan - Chemical reviews, 2014 - ACS Publications
2. INTRODUCTION The investigation of many fundamental processes in life sciences
requires straightforward tools for fast, sensitive, reliable, and reproducible detection of …
requires straightforward tools for fast, sensitive, reliable, and reproducible detection of …
[HTML][HTML] An update on oral drug delivery via intestinal lymphatic transport
Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …
Advanced drug delivery to the lymphatic system: lipid-based nanoformulations
The delivery of drugs and bioactive compounds via the lymphatic system is complex and
dependent on the physiological uniqueness of the system. The lymphatic route plays an …
dependent on the physiological uniqueness of the system. The lymphatic route plays an …
Nanoparticle drug delivery systems designed to improve cancer vaccines and immunotherapy
Recent studies have demonstrated great therapeutic potential of educating and unleashing
our own immune system for cancer treatment. However, there are still major challenges in …
our own immune system for cancer treatment. However, there are still major challenges in …
Self-microemulsifying drug delivery system (SMEDDS)–challenges and road ahead
S Dokania, AK Joshi - Drug delivery, 2015 - Taylor & Francis
Self-microemulsifying drug delivery system (SMEDDS) has emerged as a vital strategy to
formulate poor water soluble compounds for bioavailability enhancement. However, certain …
formulate poor water soluble compounds for bioavailability enhancement. However, certain …
Development of vaccine formulations: past, present, and future
The current situation, heavily influenced by the ongoing pandemic, puts vaccines back into
the spotlight. However, the conventional and traditional vaccines present disadvantages …
the spotlight. However, the conventional and traditional vaccines present disadvantages …
Functional roles of magnetic nanoparticles for the identification of metastatic lymph nodes in cancer patients
Y Yan, Y Liu, T Li, Q Liang, A Thakur, K Zhang… - Journal of …, 2023 - Springer
Staging lymph nodes (LN) is crucial in diagnosing and treating cancer metastasis.
Biotechnologies for the specific localization of metastatic lymph nodes (MLNs) have …
Biotechnologies for the specific localization of metastatic lymph nodes (MLNs) have …
Amalgamated Microneedle Array Bearing Ribociclib-Loaded Transfersomes Eradicates Breast Cancer via CD44 Targeting
HR+/HER2–metastatic breast cancer (MBC) is one of the most common and life-threatening
conditions diagnosed in women. The endocrine therapy using an orally active CDK4/6 …
conditions diagnosed in women. The endocrine therapy using an orally active CDK4/6 …