Chronic GPER activation prevents ischemia/reperfusion injury in ovariectomized rats

AM Ibañez, LFG Arbeláez, AC Pardo, S Mosca… - … et Biophysica Acta (BBA …, 2022 - Elsevier
During menopause women are exposed to an increase in cardiovascular risk. G protein-
coupled estrogen receptor (GPER) is known to mediate several of the protective effects of …

In vivo Overexpression of Electrogenic Sodium/Bicarbonate Cotransporter (NBCe1) by AAV9 Modifies the Cardiac Action Potential and the QT Interval in Mice

RA Di Mattía, LA Díaz Zegarra, CA Valverde… - Frontiers in …, 2022 - frontiersin.org
Cardiac cells depend on specific sarcolemmal ion transporters to assure the correct
intracellular pH regulation. The sodium/bicarbonate cotransporter (NBC) is one of the major …

The specific inhibition of the cardiac electrogenic sodium/bicarbonate cotransporter leads to cardiac hypertrophy

RA Di Mattia, LA Diaz-Zegarra, PG Blanco… - Life Sciences, 2023 - Elsevier
Two alkalinizing mechanisms coexist in cardiac myocytes to maintain intracellular pH:
sodium/bicarbonate cotransporter (electroneutral isoform NBCn1 and electrogenic isoform …

Polyunsaturated ω3 fatty acids prevent the cardiac hypertrophy in hypertensive rats

MR Zavala, ML Longarzo, RF Vazquez… - … et Biophysica Acta (BBA …, 2023 - Elsevier
It has been demonstrated that supplementation with the two main omega 3 polyunsaturated
fatty acids (ω3 FAs), docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA), leads …

Clinical Characteristics and Risk factors of Acute Myocardial Infarction in the Elderly after Hip Fracture: A Retrospective Study

Y Zhang, M Fu, Z Hou, Z Wang, Y Zhang - 2022 - researchsquare.com
Background: The purpose of this retrospective study is to investigate the characteristics and
determine the risk factors of Acute Myocardial Infarction (AMI) after hip fracture in the Elderly …

El estudio de la disfunción del cotransportador sodio/bicarbonato electrogénico como causa del desarrollo de la hipertrofia cardíaca

RA Di Mattia - 2022 - sedici.unlp.edu.ar
Para el correcto funcionamiento de una célula es de vital importancia el mantenimiento de
la homeostasis. En particular, en un miocito cardiaco, un descenso del pHi por debajo de 7 …