[HTML][HTML] Evaluation of the association of chronic inflammation and cancer: Insights and implications

M Nigam, AP Mishra, VK Deb, DB Dimri, V Tiwari… - Biomedicine & …, 2023 - Elsevier
Among the most extensively researched processes in the development and treatment of
cancer is inflammatory condition. Although acute inflammation is essential for the wound …

Aging, oxidative stress and degenerative diseases: mechanisms, complications and emerging therapeutic strategies

MR Chaudhary, S Chaudhary, Y Sharma, TA Singh… - Biogerontology, 2023 - Springer
Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis

HS Tuli, J Kaur, K Vashishth, K Sak, U Sharma… - Archives of …, 2023 - Springer
ROS include hydroxyl radicals (HO.), superoxide (O2..), and hydrogen peroxide (H2O2).
ROS are typically produced under physiological conditions and play crucial roles in living …

[HTML][HTML] Application of 3D-printed hydrogels in wound healing and regenerative medicine

M Deptuła, M Zawrzykraj, J Sawicka… - Biomedicine & …, 2023 - Elsevier
Hydrogels are three-dimensional polymer networks with hydrophilic properties. The
modifiable properties of hydrogels and the structure resembling living tissue allow their …

The impact of oxidative stress and AKT pathway on cancer cell functions and its application to natural products

JP Shiau, YT Chuang, JY Tang, KH Yang, FR Chang… - Antioxidants, 2022 - mdpi.com
Oxidative stress and AKT serine-threonine kinase (AKT) are responsible for regulating
several cell functions of cancer cells. Several natural products modulate both oxidative …

[HTML][HTML] Geniposide ameliorates glucocorticoid-induced osteoblast apoptosis by activating autophagy

J Huang, Y Ye, Y Xiao, Q Ren, Q Zhou, M Zhong… - Biomedicine & …, 2022 - Elsevier
Long-term exposure to glucocorticoid (GC) contributes to the development of osteoporosis
(OP), which is correlated with the risk of fracture. Pathologically, GC-induced bone loss is …

Targeting the interplay of autophagy and ROS for cancer therapy: An updated overview on phytochemicals

L Dong, J He, L Luo, K Wang - Pharmaceuticals, 2023 - mdpi.com
Autophagy is an evolutionarily conserved self-degradation system that recycles cellular
components and damaged organelles, which is critical for the maintenance of cellular …

Impacts of oxidative stress and PI3K/AKT/mTOR on metabolism and the future direction of investigating fucoidan-modulated metabolism

JP Shiau, YT Chuang, YB Cheng, JY Tang, MF Hou… - Antioxidants, 2022 - mdpi.com
The critical factors for regulating cancer metabolism are oxidative stress and
phosphoinositide-3-kinase/AKT serine-threonine kinase/mechanistic target of the rapamycin …

[HTML][HTML] Celastrol inhibits rheumatoid arthritis by inducing autophagy via inhibition of the PI3K/AKT/mTOR signaling pathway

J Yang, J Liu, J Li, M Jing, L Zhang, M Sun… - International …, 2022 - Elsevier
Objective Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder of the
synovial joints. Celastrol (Cel) is a quinone-methylated triterpenoid extracted from …

Baicalein inhibits apoptosis and autophagy induced by chlorpyrifos exposure to kidney of Cyprinus carpio through activation of PI3K/AKT pathway

Q Wu, W Yang, Y Bi, Y Yao, C Li, X Li - Pesticide biochemistry and …, 2023 - Elsevier
Chlorpyrifos (CPF), a widely used organophosphate pesticide that has caused large-scale
contamination globally, has become a major concern. Baicalein (BAI), as a flavonoid extract …