[HTML][HTML] Evaluation of the association of chronic inflammation and cancer: Insights and implications
Among the most extensively researched processes in the development and treatment of
cancer is inflammatory condition. Although acute inflammation is essential for the wound …
cancer is inflammatory condition. Although acute inflammation is essential for the wound …
Aging, oxidative stress and degenerative diseases: mechanisms, complications and emerging therapeutic strategies
MR Chaudhary, S Chaudhary, Y Sharma, TA Singh… - Biogerontology, 2023 - Springer
Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …
biological progression involving various genetic, environmental, and lifestyle factors. The …
Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis
ROS include hydroxyl radicals (HO.), superoxide (O2..), and hydrogen peroxide (H2O2).
ROS are typically produced under physiological conditions and play crucial roles in living …
ROS are typically produced under physiological conditions and play crucial roles in living …
[HTML][HTML] Application of 3D-printed hydrogels in wound healing and regenerative medicine
Hydrogels are three-dimensional polymer networks with hydrophilic properties. The
modifiable properties of hydrogels and the structure resembling living tissue allow their …
modifiable properties of hydrogels and the structure resembling living tissue allow their …
The impact of oxidative stress and AKT pathway on cancer cell functions and its application to natural products
Oxidative stress and AKT serine-threonine kinase (AKT) are responsible for regulating
several cell functions of cancer cells. Several natural products modulate both oxidative …
several cell functions of cancer cells. Several natural products modulate both oxidative …
[HTML][HTML] Geniposide ameliorates glucocorticoid-induced osteoblast apoptosis by activating autophagy
J Huang, Y Ye, Y Xiao, Q Ren, Q Zhou, M Zhong… - Biomedicine & …, 2022 - Elsevier
Long-term exposure to glucocorticoid (GC) contributes to the development of osteoporosis
(OP), which is correlated with the risk of fracture. Pathologically, GC-induced bone loss is …
(OP), which is correlated with the risk of fracture. Pathologically, GC-induced bone loss is …
Targeting the interplay of autophagy and ROS for cancer therapy: An updated overview on phytochemicals
L Dong, J He, L Luo, K Wang - Pharmaceuticals, 2023 - mdpi.com
Autophagy is an evolutionarily conserved self-degradation system that recycles cellular
components and damaged organelles, which is critical for the maintenance of cellular …
components and damaged organelles, which is critical for the maintenance of cellular …
Impacts of oxidative stress and PI3K/AKT/mTOR on metabolism and the future direction of investigating fucoidan-modulated metabolism
The critical factors for regulating cancer metabolism are oxidative stress and
phosphoinositide-3-kinase/AKT serine-threonine kinase/mechanistic target of the rapamycin …
phosphoinositide-3-kinase/AKT serine-threonine kinase/mechanistic target of the rapamycin …
[HTML][HTML] Celastrol inhibits rheumatoid arthritis by inducing autophagy via inhibition of the PI3K/AKT/mTOR signaling pathway
J Yang, J Liu, J Li, M Jing, L Zhang, M Sun… - International …, 2022 - Elsevier
Objective Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder of the
synovial joints. Celastrol (Cel) is a quinone-methylated triterpenoid extracted from …
synovial joints. Celastrol (Cel) is a quinone-methylated triterpenoid extracted from …
Baicalein inhibits apoptosis and autophagy induced by chlorpyrifos exposure to kidney of Cyprinus carpio through activation of PI3K/AKT pathway
Q Wu, W Yang, Y Bi, Y Yao, C Li, X Li - Pesticide biochemistry and …, 2023 - Elsevier
Chlorpyrifos (CPF), a widely used organophosphate pesticide that has caused large-scale
contamination globally, has become a major concern. Baicalein (BAI), as a flavonoid extract …
contamination globally, has become a major concern. Baicalein (BAI), as a flavonoid extract …