[HTML][HTML] Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy

Y Liu, Y Li, Y Wang, C Lin, D Zhang, J Chen… - Journal of Hematology & …, 2022 - Springer
Vascular endothelial growth factor receptors (VEGFRs) are a family of receptor protein
tyrosine kinases that play an important role in the regulation of tumor-induced angiogenesis …

[HTML][HTML] Matrine: a promising natural product with various pharmacological activities

H Zhang, L Chen, X Sun, Q Yang, L Wan… - Frontiers in …, 2020 - frontiersin.org
Matrine is an alkaloid isolated from the traditional Chinese medicine Sophora flavescens
Aiton. At present, a large number of studies have proved that matrine has an anticancer …

Matrine: A review of its pharmacology, pharmacokinetics, toxicity, clinical application and preparation researches

X Li, Z Tang, L Wen, C Jiang, Q Feng - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance “Dogel ebs” was known as Sophora flavescens Ait., which
has been widely utilized in the clinical practice of traditional Chinese Mongolian herbal …

[HTML][HTML] Research advances on matrine

XY Sun, LY Jia, Z Rong, X Zhou, LQ Cao, AH Li… - Frontiers in …, 2022 - frontiersin.org
Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora
flavescentis, Sophora alopecuroides, Sophora root, etc. It has the dual advantages of …

[HTML][HTML] Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives

HI Abd-Alla, D Souguir, MO Radwan - Archives of pharmacal research, 2021 - Springer
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third
largest family of flowering plants. The genus Sophora comprises approximately 52 species …

[HTML][HTML] Effects and mechanisms of natural alkaloids for prevention and treatment of osteoporosis

B Lin, P Xu, J Zheng, X Deng, Q Ye, Z Huang… - Frontiers in …, 2022 - frontiersin.org
Natural alkaloids are polycyclic, nitrogen-containing, and basic compounds obtained from
plants. In this review, the advances in bioactive alkaloids with respect to their chemical …

Quinolizidine-type alkaloids: chemodiversity, occurrence, and bioactivity

W Cely-Veloza, MJ Kato, E Coy-Barrera - ACS omega, 2023 - ACS Publications
Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …

[HTML][HTML] Pharmacological mechanism of natural drugs and their active ingredients in the treatment of arrhythmia via calcium channel regulation

X Zhang, Y Gao, Y Zhou, Z Liu, R Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Arrhythmia is characterized by abnormal heartbeat rhythms and frequencies caused by
heart pacing and conduction dysfunction. Arrhythmia is the leading cause of death in …

[HTML][HTML] Correlation in endophytic fungi community diversity and bioactive compounds of Sophora alopecuroides

M Ju, Q Zhang, R Wang, S Yan, Z Li, P Li… - Frontiers in …, 2022 - frontiersin.org
Sophora alopecuroides L. is a traditional Chinese medicine used for the treatment of several
different disease states including bacillary dysentery and enteritis. But importantly, it also …

[HTML][HTML] A review on recent advances in aloperine research: pharmacological activities and underlying biological mechanisms

H Zhou, J Li, F Sun, F Wang, M Li, Y Dong… - Frontiers in …, 2020 - frontiersin.org
Aloperine, a quinolizidine-type alkaloid, was first isolated from the seeds and leaves of
herbal plant, Sophora alopecuroides L. Empirically, Sophora alopecuroides L. is …