Molecular mechanisms and treatment strategies for methamphetamine‑induced neurodegeneration, inflammation and neurotoxicity

S Omidvari, Z Azimzadeh, F Rashnoo… - Acta neurobiologiae …, 2023 - ane.pl
Methamphetamine (METH) is a highly addictive psychostimulant known for its profound
impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by …

[HTML][HTML] Exploring amygdala structural changes and signaling pathways in postmortem brains: consequences of long-term methamphetamine addiction

Z Azimzadeh, S Omidvari, S Niknazar… - Anatomy & Cell …, 2023 - synapse.koreamed.org
Methamphetamine (METH) can potentially disrupt neurotransmitters activities in the central
nervous system (CNS) and cause neurotoxicity through various pathways. These pathways …

[HTML][HTML] Natural products as the therapeutic strategies for addiction

R Yu, DL Kong, C Liao, YJ Yu, ZW He… - Biomedicine & …, 2024 - Elsevier
Abstract World Drug Report 2023 concluded that 296 million people abused drugs, 39.5
million became addiction and 494,000 died as a direct or indirect result of addiction …

[HTML][HTML] Oxidative stress and inflammatory biomarkers in people with methamphetamine use disorder

Ç Turan, G Şenormancı, S Neşelioğlu… - Clinical …, 2023 - ncbi.nlm.nih.gov
Objective This study aimed to investigate the blood serum levels of biomarkers specifying
oxidative stress status and systemic inflammation between people using methamphetamine …

[HTML][HTML] Methamphetamine exposure drives cell cycle exit and aberrant differentiation in rat hippocampal-derived neurospheres

S Wang, L Wang, Q Bu, Q Wei, L Jiang, Y Dai… - Frontiers in …, 2023 - frontiersin.org
Introduction: Methamphetamine (METH) abuse by pregnant drug addicts causes toxic effects
on fetal neurodevelopment; however, the mechanism underlying such effect of METH is …

Calcitriol protects against reductions in striatal serotonin in rats treated with neurotoxic doses of methamphetamine

WA Cass, LE Peters - Neurochemistry International, 2023 - Elsevier
The present experiments were designed to examine the ability of calcitriol to protect against
methamphetamine (METH)-induced reductions in striatal serotonin (5-HT) release and …

Triggering Receptor Expressed on Myeloid Cells 2 Deficiency Exacerbates Methamphetamine-Induced Activation of Microglia and Neuroinflammation

Y Peng, G Yang, S Wang, W Lin, L Zhu… - International …, 2024 - journals.sagepub.com
Methamphetamine (METH) is a highly addictive psychostimulant and one of the most widely
abused drugs worldwide. The continuous use of METH eventually leads to neurotoxicity and …

What Happens When Methamphetamine Is Added to Nutrients of Cell Culture Medium? In Vitro Assessment of Morphological, Growth and Differential Potential of …

N Mohammdzadeh, D Mehrabani, S Zare… - International Journal of …, 2022 - ijns.sums.ac.ir
Background: Methamphetamine use and misuse cause severe side effects in different body
organs and are associated with socioeconomic consequences. This study aimed to …

[HTML][HTML] Glutamate-Mediated Excitotoxicity in the Pathogenesis and Treatment of Neurodevelopmental and Adult Mental Disorders

N Nicosia, M Giovenzana, P Misztak… - International Journal of …, 2024 - mdpi.com
Glutamate is the main excitatory neurotransmitter in the brain wherein it controls cognitive
functional domains and mood. Indeed, brain areas involved in memory formation and …

[HTML][HTML] Identification of Methamphetamine Abusers Can Be Supported by EEG-Based Wavelet Transform and BiLSTM Networks

H Zhou, J Zhang, J Gao, X Zeng, X Min, H Zhan… - Brain Topography, 2024 - Springer
Methamphetamine (MA) is a neurological drug, which is harmful to the overall brain
cognitive function when abused. Based on this property of MA, people can be divided into …