Nociplastic pain is the semantic term suggested by the international community of pain
researchers to describe a third category of pain that is mechanistically distinct from …

Fibromyalgia is characterized by chronic widespread pain, fatigue, sleep disturbances and
functional symptoms. The etiopathogenesis, diagnostic criteria and classification criteria of …

Fibromyalgia (FM) is a syndrome that does not present a well-defined underlying organic
disease. FM is a condition which has been associated with diseases such as infections …

Tricyclic antidepressants and serotonin noradrenaline reuptake inhibitors are used to treat
chronic pain, such as neuropathic pain. Why antidepressants are effective for treatment of …

In this experimental randomized placebo-controlled 4-way crossover trial, we explored the
analgesic effects of inhaled pharmaceutical-grade cannabis in 20 chronic pain patients with …

This review article presents and summarizes up-to-date literature on the clinical
manifestations, diagnosis, pathophysiological mechanisms, and treatment options for …

In addition to central hyperexcitability and impaired top–down modulation, chronic
inflammation probably plays a role in the pathophysiology of fibromyalgia (FM). Indeed, on …

Introduction. Fibromyalgia syndrome (FMS) is a pain disorder with an estimated prevalence
of 1–5%. It is associated with a variety of somatic and psychological disorders. Its exact …

Tricyclic Antidepressants - StatPearls - NCBI Bookshelf Your browser does not support the NLM
PubReader view. Go to this page to see a list of supported browsers or return to the regular …

Low back pain is one of the four most common disorders in all regions, and the greatest
contributor to disability worldwide, adding 10.7% of total years lost due to this health state …