Defining cardiovascular toxicities of cancer therapies: an International Cardio-Oncology Society (IC-OS) consensus statement

J Herrmann, D Lenihan, S Armenian… - European heart …, 2022 - academic.oup.com
Abstract The discipline of Cardio-Oncology has seen tremendous growth over the past
decade. It is devoted to the cardiovascular (CV) care of the cancer patient, especially to the …

Inequity in cardio‐oncology: identifying disparities in cardiotoxicity and links to cardiac and cancer outcomes

RE Ohman, EH Yang, ML Abel - Journal of the American Heart …, 2021 - Am Heart Assoc
Minority and underresourced communities experience disproportionately high rates of fatal
cancer and cardiovascular disease. The intersection of these disparities within the …

Sirtuin 3: Emerging therapeutic target for cardiovascular diseases

M Cao, Q Zhao, X Sun, H Qian, S Lyu, R Chen… - Free Radical Biology …, 2022 - Elsevier
Acetylation is one of the most important methods of modification that lead to a change in the
function of proteins. In humans, metabolic enzymes commonly undergo acetylation, which …

[HTML][HTML] ACEI/ARB and beta-blocker therapies for preventing cardiotoxicity of antineoplastic agents in breast cancer: a systematic review and meta-analysis

Y Gao, R Wang, J Jiang, Y Hu, H Li, Y Wang - Heart Failure Reviews, 2023 - Springer
Anthracyclines and trastuzumab are widely used to treat breast cancer but increase the risk
of cardiomyopathy and heart failure. With the use of trastuzumab and anthracycline …

[HTML][HTML] Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans

JM Vicencio, R Evans, R Green, Z An, J Deng… - Cell Death & …, 2022 - nature.com
Over the past decade, immunotherapy delivered novel treatments for many cancer types.
However, lung cancer still leads cancer mortality, and non-small-cell lung carcinoma …

[HTML][HTML] Cardiotoxicity induced by immune checkpoint inhibitors: what a cardio-oncology team should know and do

C Zito, R Manganaro, G Ciappina, CC Spagnolo… - Cancers, 2022 - mdpi.com
Simple Summary Immune checkpoint inhibitors, including monoclonal antibodies directed
against the programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) …

Long-term follow-up assessment of cardiac safety in SAFE-HEaRt, a clinical trial evaluating the use of HER2-targeted therapies in patients with breast cancer and …

K Khoury, F Lynce, A Barac, X Geng, C Dang… - Breast cancer research …, 2021 - Springer
Purpose HER2-targeted therapies are associated with cardiotoxicity which is usually
asymptomatic and reversible. We report the updated cardiac safety assessment of patients …

Cardiovascular Fellowship Training in Cardio-Obstetrics: JACC Review Topic of the Week

MB Davis, NA Bello, K Berlacher, CM Harrington… - Journal of the American …, 2023 - jacc.org
Abstract The United States has the highest maternal mortality in the developed world with
cardiovascular disease as the leading cause of pregnancy-related deaths. In response to …

[HTML][HTML] Social determinants of health in cardio-oncology: multi-level strategies to overcome disparities in care: JACC: CardioOncology state-of-the-art review

FO Baah, S Sharda, K Davidow, S Jackson… - JACC …, 2024 - Elsevier
Addressing the need for more equitable cardio-oncology care requires attention to existing
disparities in cardio-oncologic disease prevention and outcomes. This is particularly …

Competing risk analysis of cardiovascular death in patients with primary gallbladder cancer

C Chen, F Xu, S Yuan, X Zhao, M Qiao, D Han… - Cancer …, 2023 - Wiley Online Library
Background Developments in medical technology are resulting in continuous decreases in
the cancer mortality rate of patients with gallbladder cancer, while non‐cancer deaths in …