The emergence of RAS/RAF mutant clone is the main feature of EGFR inhibitor resistance in
KRAS wild-type colon cancer. However, its molecular mechanism is thought to be …

Introduction Breast cancer is the most common type of cancer seen in women in western
countries. Thus, diagnostic modalities sensitive to early-stage breast cancer are needed …

Currently, the assay of whole blood has emerged as an important tool in modern biomedical
research such as clinical diagnostics, drug discovery, and biodefense. Whole blood is a …

Biomarker detection based on nanowire biosensors has attracted a significant amount of
research effort in recent years. However, only very limited research work has been directed …

Triple negative breast cancer is a heterogeneous group of tumors, lacking the expression of
estrogen, progesterone and HER-2 receptors. As frequency, it accounts about 15–20% of all …

This randomized, multicenter study compared the efficacy of docetaxel with or without
capecitabine following fluorouracil/epirubicin/cyclophosphamide (FEC) therapy in operable …

Cancer is a disease characterized by a very little apoptosis, ie, genetically programmed cell
death. Aberrations in apoptotic pathways are central to tumorigenesis, tumor progression …

Background This study aimed to investigate the clinical utility of serum and histological MMP-
9 detection during neoadjuvant chemotherapy (NAC) for triple-negative breast cancer …

Background: Currently, serum biomarkers, which are sufficiently sensitive and specific for
early detection and risk classification of gastric adenocarcinoma do not exist. Therefore, this …

Background IFN-γ is presently the only soluble immunological marker used to help diagnose
latent Mycobacterium tuberculosis (M. tb) infection. However, IFN-γ is not available to …