Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …

Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …

Cerebral malaria is a deadly outcome of infection by Plasmodium falciparum, occurring
when parasite-infected erythrocytes accumulate in the brain. These erythrocytes display …

The variant antigen Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1),
which is expressed on the surface of P. falciparum-infected red blood cells, is a critical …

The clinical outcome of Plasmodium falciparum infections ranges from asymptomatic
parasitemia to severe malaria syndromes associated with high mortality. The virulence of P …

Plasmodium falciparum causes the most severe form of malaria and is responsible for
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …

Cerebral malaria (CM) is caused by the binding of Plasmodium falciparum–infected
erythrocytes (IEs) to the brain microvasculature, leading to inflammation, vessel occlusion …

The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family plays a central
role in antigenic variation and cytoadhesion of P. falciparum infected erythrocytes. PfEMP1 …

Cerebral Plasmodium falciparum malaria is characterized by adhesion of infected
erythrocytes (IEs) to the cerebral microvasculature. This has been linked to parasites …

Malaria is a significant threat throughout the developing world. Among the most fascinating
aspects of the protozoan parasites responsible for this disease are the methods they employ …