Osteoblast Differentiation and Bone Matrix Formation In Vivo and In Vitro

HC Blair, QC Larrouture, Y Li, H Lin… - … Engineering Part B …, 2017 - liebertpub.com
We review the characteristics of osteoblast differentiation and bone matrix synthesis. Bone in
air breathing vertebrates is a specialized tissue that developmentally replaces simpler solid …

[HTML][HTML] Importance of dietary phosphorus for bone metabolism and healthy aging

J Serna, C Bergwitz - Nutrients, 2020 - mdpi.com
Inorganic phosphate (Pi) plays a critical function in many tissues of the body: for example, as
part of the hydroxyapatite in the skeleton and as a substrate for ATP synthesis. Pi is the main …

[HTML][HTML] Vitamin D supplementation in pregnancy and lactation and infant growth

DE Roth, SK Morris, S Zlotkin… - New England journal …, 2018 - Mass Medical Soc
Background It is unclear whether maternal vitamin D supplementation during pregnancy and
lactation improves fetal and infant growth in regions where vitamin D deficiency is common …

Tumour-induced osteomalacia

S Minisola, M Peacock, S Fukumoto… - Nature reviews Disease …, 2017 - nature.com
Abstract Tumour-induced osteomalacia (TIO), also known as oncogenic osteomalacia, is a
rare paraneoplastic disorder caused by tumours that secrete fibroblast growth factor 23 …

Phosphate metabolism in health and disease

M Peacock - Calcified tissue international, 2021 - Springer
Phosphorus, a 5A element with atomic weight of 31, comprises just over 0.6% of the
composition by weight of plants and animals. Three isotopes are available for studying …

Role of phosphate sensing in bone and mineral metabolism

S Chande, C Bergwitz - Nature Reviews Endocrinology, 2018 - nature.com
Inorganic phosphate (Pi) is essential for signal transduction and cell metabolism, and is also
an essential structural component of the extracellular matrix of the skeleton. Pi is sensed in …

Calcified nodules in retinal drusen are associated with disease progression in age-related macular degeneration

ACS Tan, MG Pilgrim, S Fearn, S Bertazzo… - Science translational …, 2018 - science.org
Drusen are lipid-, mineral-, and protein-containing extracellular deposits that accumulate
between the basal lamina of the retinal pigment epithelium (RPE) and Bruch's membrane …

Vitamin D and phosphate interactions in health and disease

NS Akimbekov, I Digel, DK Sherelkhan… - … : From Physiology to …, 2022 - Springer
Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis,
maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as …

Phosphate transport in epithelial and nonepithelial tissue

N Hernando, K Gagnon, E Lederer - Physiological reviews, 2021 - journals.physiology.org
Phosphate is an essential nutrient for life and is a critical component of bone formation, a
major signaling molecule, and structural component of cell walls. Phosphate is also a …

[HTML][HTML] Phosphorus nutrition of growing pigs

H Zhai, O Adeola, J Liu - Animal Nutrition, 2022 - Elsevier
Phosphorus (P) is an essential nutrient for diverse biological processes, which aggregate to
the animal's requirement for P, and nutritionists strive to meet this requirement accurately …