This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Paracetamol (acetaminophen) is the most commonly used over‐the‐counter (OTC) drug in
the world. Despite its popularity and use for many years, the safety of its application and its …

Background The neuroinflammatory response following traumatic brain injury (TBI) is known
to be a key secondary injury factor that can drive ongoing neuronal injury. Despite this …

When cells undergo necrotic cell death in either physiological or pathophysiological settings
in vivo, they release highly immunogenic intracellular molecules and organelles into the …

Transient receptor potential (TRP) channels are one primary type of calcium (Ca 2+)
permeable channels, and those relevant transmembrane and intracellular TRP channels …

The recruitment of neutrophils to sites of inflammation, their battle against invading
microorganisms through phagocytosis and the release of antimicrobial agents is a highly …

It is well known that certain active ingredients of the plants of Cannabis genus, ie, the
“phytocannabinoids”[pCBs; eg,(−)-trans-Δ9-tetrahydrocannabinol (THC),(−)-cannabidiol …

In the current post-antibiotic era, botanicals represent one of the most employed nutritional
strategies to sustain antibiotic-free and no-antibiotic-ever production. Botanicals can be …

Calcium is the most abundant mineral in the human body and is central to many
physiological processes, including immune system activation and maintenance. Studies …

Phenotypic polarization of macrophages is deemed essential in innate immunity and various
pathophysiological conditions. We have now determined key aspects of the molecular …