Lymph node targeting strategies to improve vaccination efficacy

H Jiang, Q Wang, X Sun - Journal of Controlled Release, 2017 - Elsevier
With the rapid development of nanotechnology as well as growing interest in
immunotherapy, a great number of vaccine delivery vehicles have been explored in order to …

Adjuvant physiochemistry and advanced nanotechnology for vaccine development

H Ren, W Jia, Y Xie, M Yu, Y Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

Targeted codelivery of an antigen and dual agonists by hybrid nanoparticles for enhanced cancer immunotherapy

L Zhang, S Wu, Y Qin, F Fan, Z Zhang, C Huang… - Nano …, 2019 - ACS Publications
Among approaches of current cancer immunotherapy, a dendritic cell (DC)-targeted vaccine
based on nanotechnology could be a promising way to efficiently induce potent immune …

[HTML][HTML] Nano toolbox in immune modulation and nanovaccines

M Azharuddin, GH Zhu, A Sengupta, J Hinkula… - Trends in …, 2022 - cell.com
Despite the great success of vaccines over two centuries, the conventional strategy is based
on attenuated/altered microorganisms. However, this is not effective for all microbes and …

Emerging nano‐/microapproaches for cancer immunotherapy

Y Mi, CT Hagan IV, BG Vincent, AZ Wang - Advanced Science, 2019 - Wiley Online Library
Cancer immunotherapy has achieved remarkable clinical efficacy through recent advances
such as chimeric antigen receptor‐T cell (CAR‐T) therapy, immune checkpoint blockade …

[HTML][HTML] Recent advances and challenges of repurposing nanoparticle-based drug delivery systems to enhance cancer immunotherapy

S Lim, J Park, MK Shim, W Um, HY Yoon, JH Ryu… - Theranostics, 2019 - ncbi.nlm.nih.gov
Cancer immunotherapy is an attractive treatment option under clinical settings. However, the
major challenges of immunotherapy include limited patient response, limited tumor …

Harnessing innate immunity using biomaterials for cancer immunotherapy

DY Lee, K Huntoon, Y Wang, W Jiang… - Advanced …, 2021 - Wiley Online Library
The discovery of immune checkpoint blockade has revolutionized the field of immuno‐
oncology and established the foundation for developing various new therapies that can …

Implantable synthetic immune niche for spatiotemporal modulation of tumor‐derived immunosuppression and systemic antitumor immunity: postoperative …

H Phuengkham, C Song, SH Um, YT Lim - Advanced Materials, 2018 - Wiley Online Library
The development of biomaterial‐based immune niches that can modulate
immunosuppressive factors in tumor microenvironment (TME) will be a key technology for …

Engineering nanoparticle strategies for effective cancer immunotherapy

HY Yoon, ST Selvan, Y Yang, MJ Kim, DK Yi, IC Kwon… - Biomaterials, 2018 - Elsevier
Cancer immunotherapy has been emerging in recent years, due to the inherent nature of the
immune system. Although recent successes of immunotherapeutics in clinical application …

Modulating the immune system through nanotechnology

TG Dacoba, A Olivera, D Torres… - Seminars in …, 2017 - Elsevier
Nowadays, nanotechnology-based modulation of the immune system is presented as a
cutting-edge strategy, which may lead to significant improvements in the treatment of severe …