Lymph nodes (LNs) are tissues of the immune system that house leukocytes, making them
targets of interest for a variety of therapeutic immunomodulation applications. However …

Despite the significant efforts in developing cancer vaccines, there are still numerous
challenges that need to be addressed to ensure their clinical efficacy. Herein, a lymphatic …

The continuing challenges that limit effectiveness of tumor therapeutic vaccines were high
heterogeneity of tumor immunogenicity, low bioactivity of antigens, as well as insufficient …

Immunotherapy has emerged as a potent strategy in cancer treatment, with many approved
drugs and modalities in the development stages. Despite its promise, immunotherapy is not …

Recently, tumor immunotherapy has achieved great progress in the treatment of
hematological and solid neoplasms. The DC vaccines, KLH-conjugated vaccines or …

Tumor-targeted ligand modification and nanosized coloaded drug delivery systems are
promising for cancer therapy. In this study, we showed that coix seed oil and tripterine …

Aim: To design lympho-targeted nanocarriers with the capacity to enhance the activity of
associated drugs/antigens whose target is within the lymphatic system. Materials & methods …

Particle size and surface properties are crucial for lymphatic drainage (LN), dendritic cell
(DC) uptake, DC maturation, and antigen cross-presentation induced by nanovaccine …

Hydrogel has been proven to have the ability to deliver antigens continuously to achieve
slow vaccine delivery, which makes it a promising candidate for an adjuvant delivery …

Although this is an era of pandemics and many devastating diseases, this is also a time
when bionanotechnology flourishes, illuminating a multidisciplinary field where vaccines are …