[HTML][HTML] Can supplementation with vitamin D reduce the risk or modify the course of autoimmune diseases? A systematic review of the literature

A Antico, M Tampoia, R Tozzoli, N Bizzaro - Autoimmunity reviews, 2012 - Elsevier
OBJECTIVE: To evaluate whether vitamin D levels are related to the risk of developing
autoimmune diseases and whether supplementation with vitamin D can modify the course of …

Does vitamin D affect risk of developing autoimmune disease?: a systematic review

MA Kriegel, JAE Manson, KH Costenbader - Seminars in arthritis and …, 2011 - Elsevier
OBJECTIVES:: We evaluated the epidemiologic evidence that vitamin D may be related to
human autoimmune disease risk. METHODS:: PubMed, limited to English from inception …

Reduction in IL-10 producing B cells (Breg) in multiple sclerosis is accompanied by a reduced naive/memory Breg ratio during a relapse but not in remission

S Knippenberg, E Peelen, J Smolders… - Journal of …, 2011 - Elsevier
In this study, we assessed B cell subsets, including Bregs, during stable and active disease
in relapsing remitting multiple sclerosis (RRMS) patients and related B cell subsets to …

Effects of neurological disorders on bone health

RR Kelly, SJ Sidles, AC LaRue - Frontiers in psychology, 2020 - frontiersin.org
Neurological diseases, particularly in the context of aging, have serious impacts on quality of
life and can negatively affect bone health. The brain-bone axis is critically important for …

Osteopontin (OPN) as a CSF and blood biomarker for multiple sclerosis: A systematic review and meta-analysis

E Agah, A Zardoui, A Saghazadeh, M Ahmadi… - PLoS …, 2018 - journals.plos.org
Identifying a reliable biomarker may accelerate diagnosis of multiple sclerosis (MS) and lead
to early management of the disease. Accumulating evidence suggest that cerebrospinal fluid …

The good and the bad of neuroinflammation in multiple sclerosis

M Naegele, R Martin - Handbook of clinical neurology, 2014 - Elsevier
Multiple sclerosis (MS) is the most common inflammatory, demyelinating, neurodegenerative
disorder of the central nervous system (CNS). It is widely considered a T-cell mediated …

Vitamin D in the healthy and inflamed central nervous system: access and function

J Smolders, SM Moen, J Damoiseaux, I Huitinga… - Journal of the …, 2011 - Elsevier
High exposure to vitamin D may protect against development and progression of multiple
sclerosis (MS), possibly through the immunomodulatory properties of its biologically active …

Cholecalciferol plus calcium suppresses abnormal PBMC reactivity in patients with multiple sclerosis

S Kimball, R Vieth, HM Dosch, A Bar-Or… - The Journal of …, 2011 - academic.oup.com
Context: The active metabolite of vitamin D, 1, 25-dihydroxyvitamin D [1, 25 (OH) 2D], is a
potent modulator of immune cells in vitro. Objective: Our objective was to determine whether …

Increased levels of IL-23 and osteopontin in serum and cerebrospinal fluid of multiple sclerosis patients

SR Wen, GJ Liu, RN Feng, FC Gong, H Zhong… - Journal of …, 2012 - Elsevier
Osteopontin (OPN) and interleukin-23 (IL-23) are pro-inflammatory cytokines proposed to
play central roles to the development of multiple sclerosis (MS). The aim of this study was to …

Osteoporosis and multiple sclerosis: risk factors, pathophysiology, and therapeutic interventions

S Gupta, I Ahsan, N Mahfooz, N Abdelhamid… - CNS drugs, 2014 - Springer
Multiple sclerosis (MS) is a chronic inflammatory-demyelinating disease of the nervous
system. There has been mounting evidence showing that MS is associated with increased …