[HTML][HTML] Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials
P Gevaert, TA Omachi, J Corren, J Mullol, J Han… - Journal of Allergy and …, 2020 - Elsevier
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by IgE
hyperproduction and eosinophilic inflammation. The anti-IgE antibody, omalizumab, has …
hyperproduction and eosinophilic inflammation. The anti-IgE antibody, omalizumab, has …
Inflammation and endotyping in chronic rhinosinusitis—a paradigm shift
S Ahern, A Cervin - Medicina, 2019 - mdpi.com
Chronic rhinosinusitis (CRS) is a heterogeneous chronic inflammatory condition of the
paranasal sinuses and nasal passage. It is characterized as inflammation of the sinonasal …
paranasal sinuses and nasal passage. It is characterized as inflammation of the sinonasal …
Nasal polyposis: insights in epithelial-mesenchymal transition and differentiation of polyp mesenchymal stem cells
Chronic rhinosinusitis is a common inflammatory disease of paranasal sinuses, which
causes rhinorrhea, nasal congestion, and hyposmia. The genetic predisposition or the …
causes rhinorrhea, nasal congestion, and hyposmia. The genetic predisposition or the …
[HTML][HTML] Dupilumab improves upper and lower airway disease control in chronic rhinosinusitis with nasal polyps and asthma
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) and type 2 asthma share
the same inflammatory pathophysiology and are frequent comorbidities. Dupilumab, a fully …
the same inflammatory pathophysiology and are frequent comorbidities. Dupilumab, a fully …
Defining the efficacy of omalizumab in nasal polyposis: a POLYP 1 and POLYP 2 subgroup analysis
C Damask, M Chen, CTJ Holweg… - American Journal of …, 2022 - journals.sagepub.com
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous
disease with variable underlying pathophysiologies. Numerous patient factors have been …
disease with variable underlying pathophysiologies. Numerous patient factors have been …
Management of patients with chronic rhinosinusitis during the COVID‐19 pandemic—An EAACI position paper
Background Chronic rhinosinusitis is regarded as a chronic airway disease. According to
WHO recommendations, it may be a risk factor for COVID‐19 patients. In most CRSwNP …
WHO recommendations, it may be a risk factor for COVID‐19 patients. In most CRSwNP …
Surgery in nasal polyp patients: outcome after a minimum observation of 10 years
S Vlaminck, F Acke, E Prokopakis… - American Journal of …, 2021 - journals.sagepub.com
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) often requires surgery, but
recurrence even after surgery is common. Recurrence rates largely vary in literature and …
recurrence even after surgery is common. Recurrence rates largely vary in literature and …
Real-life effectiveness of mepolizumab in refractory chronic rhinosinusitis with nasal polyps
MS Domínguez-Sosa, MS Cabrera-Ramírez… - Biomedicines, 2023 - mdpi.com
The aim of this study was to evaluate the efficacy of mepolizumab in patients affected by
chronic rhinosinusitis with nasal polyps (CRSwNP) in real-life. A single-center retrospective …
chronic rhinosinusitis with nasal polyps (CRSwNP) in real-life. A single-center retrospective …
[HTML][HTML] Positionspapier: Anwendung von Biologika bei chronischer Rhinosinusitis mit Polyposis nasi (CRSwNP) im deutschen Gesundheitssystem–Empfehlungen …
L Klimek, U Förster-Ruhrmann, S Becker… - Laryngo-Rhino …, 2020 - thieme-connect.com
Hintergrund Die chronische Rhinosinusitis (CRS) betrifft weltweit ca. 5–12% der
Allgemeinbevölkerung und wird traditionell eingeteilt in einen Phänotyp ohne (CRSsNP) …
Allgemeinbevölkerung und wird traditionell eingeteilt in einen Phänotyp ohne (CRSsNP) …
Type 2 immunity‐driven diseases: Towards a multidisciplinary approach
D Hassoun, O Malard, S Barbarot… - Clinical & …, 2021 - Wiley Online Library
Asthma, atopic dermatitis and chronic rhinoconjunctivitis are highly heterogeneous.
However, epidemiologic associations exist between phenotypic groups of patients. Atopic …
However, epidemiologic associations exist between phenotypic groups of patients. Atopic …