Advanced nanotechnology leading the way to multimodal imaging‐guided precision surgical therapy

C Wang, W Fan, Z Zhang, Y Wen, L Xiong… - Advanced …, 2019 - Wiley Online Library
Surgical resection is the primary and most effective treatment for most patients with solid
tumors. However, patients suffer from postoperative recurrence and metastasis. In the past …

Fluorescence guided sentinel lymph node mapping: from current molecular probes to future multimodal nanoprobes

S Hameed, H Chen, M Irfan, SZ Bajwa… - Bioconjugate …, 2018 - ACS Publications
For SLN lymph node biopsy (SLNB), SLN mapping has become a standard of care
procedure that can accurately locate the micrometastases disseminated from primary tumor …

Impact of semiconducting perylene diimide nanoparticle size on lymph node mapping and cancer imaging

Z Yang, R Tian, J Wu, Q Fan, BC Yung, G Niu… - ACS …, 2017 - ACS Publications
Semiconducting molecules of perylene diimide (PDI) with strong light absorption properties
in the near-infrared region and good biocompatibility have received increasing attention in …

Visualization of sentinel lymph nodes with mannosylated fluorescent nanodiamonds

K Kvakova, M Ondra, J Schimer, M Petrik… - Advanced Functional …, 2022 - Wiley Online Library
The present study focuses on the development of a sensitive and specific approach for the
visualization of sentinel lymph nodes draining the tumor using ultrabright 200‐nm …

Ultrabright AIEdots with tunable narrow emission for multiplexed fluorescence imaging

X Zhou, L Zhao, K Zhang, C Yang, S Li, X Kang… - Chemical …, 2023 - pubs.rsc.org
AIEgen doped fluorescent nanodots (AIEdots) have attracted lots of attention, due to their
superior characteristics as fluorescent probes, such as excellent photostability, large Stokes …

Innovations in lymph node targeting nanocarriers

J Kim, PA Archer, SN Thomas - Seminars in immunology, 2021 - Elsevier
Lymph nodes are secondary lymphoid tissues in the body that facilitate the co-mingling of
immune cells to enable and regulate the adaptive immune response. They are also tissues …

Calcium Fluoride Nanocrystals: Tracers for In Vivo 19F Magnetic Resonance Imaging

I Ashur, H Allouche‐Arnon… - Angewandte Chemie …, 2018 - Wiley Online Library
Inorganic nanocrystals (NCs) have been extensively developed for a variety of uses. The
ability to obtain high‐resolution NMR signals from the core nuclei of NCs in solution could …

[HTML][HTML] ATP-responsive and near-infrared-emissive nanocarriers for anticancer drug delivery and real-time imaging

C Qian, Y Chen, S Zhu, J Yu, L Zhang, P Feng… - Theranostics, 2016 - ncbi.nlm.nih.gov
Stimuli-responsive and imaging-guided drug delivery systems hold vast promise for
enhancement of therapeutic efficacy. Here we report an adenosine-5'-triphosphate (ATP) …

Manganese porphyrin/ICG nanoparticles as magnetic resonance/fluorescent dual-mode probes for imaging of sentinel lymph node metastasis

X Fu, S Fu, Z Cai, R Jin, C Xia, S Lui, B Song… - Journal of Materials …, 2022 - pubs.rsc.org
Diagnosis of sentinel lymph node (SLN) metastasis and its status are key parameters for
predicting overall disease prognosis. In this work, Pluronic F127 stabilized ICG/tetra (4 …

Intraoperative mapping of sentinel lymph node metastases using a clinically translated ultrasmall silica nanoparticle

MS Bradbury, M Pauliah, P Zanzonico… - Wiley …, 2016 - Wiley Online Library
The management of regional lymph nodes in patients with melanoma has undergone a
significant paradigm shift over the past several decades, transitioning from the use of more …