The stress response comprises a phylogenetically conserved set of cognitive, physiological,
and behavioral responses that evolved as a survival strategy. In this context, the memory of …

Adrenal crises are severe manifestations of adrenal insufficiency that result in hospital
admission and incur a risk of cardiovascular events, acute renal injury, and death. Evidence …

Objective Cushing's syndrome (CS) is associated with neuropsychological deficits. As the
cerebellum plays a key role in neuropsychological functions it may be affected in CS. The …

Context Glucocorticoids have potent effects on the central nervous system. However, while
patients with Cushing syndrome frequently report impairments in cognitive function, studies …

Brain structural abnormalities are often observed on magnetic resonance imaging (MRI)
scans of Cushing's syndrome patients, but the pathogenesis is not fully understood. To …

Objectives Neuropsychological deficits and hypothalamic-pituitary-adrenal (HPA) axis
dysfunction have been described in major depressive disorder (MDD). We conducted an …

Background In the last few years, quality of life (QoL) has become an outcome measure in
patients with pituitary diseases. Objective To describe the available data on QoL impairment …

Context and objective We previously found that patients with Cushing's syndrome (CS)
scored lower than controls in several domains of cognitive function and that correction of …

BACKGROUND AND PURPOSE: Cushing syndrome appears after chronic exposure to
elevated glucocorticoid levels. Cortisol excess may alter white matter microstructure. Our …

One hundred years have passed since Harvey Williams Cushing presented the first patient
with the syndrome that bears his name. In patients with Cushing's syndrome (CS), body …