[PDF][PDF] Hallmarks of aging: An expanding universe
Aging is driven by hallmarks fulfilling the following three premises:(1) their age-associated
manifestation,(2) the acceleration of aging by experimentally accentuating them, and (3) the …
manifestation,(2) the acceleration of aging by experimentally accentuating them, and (3) the …
Global epidemiology of rheumatoid arthritis
Rheumatoid arthritis (RA) is a systemic autoimmune disease that predominantly affects the
joints. The prevalence of RA varies globally, with generally a higher prevalence in …
joints. The prevalence of RA varies globally, with generally a higher prevalence in …
A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy
Increasing evidence suggests that the gut microbiome may modulate the efficacy of cancer
immunotherapy. In a B cell lymphoma patient cohort from five centers in Germany and the …
immunotherapy. In a B cell lymphoma patient cohort from five centers in Germany and the …
[PDF][PDF] Meta-hallmarks of aging and cancer
Both aging and cancer are characterized by a series of partially overlapping" hallmarks" that
we subject here to a meta-analysis. Several hallmarks of aging (ie, genomic instability …
we subject here to a meta-analysis. Several hallmarks of aging (ie, genomic instability …
[HTML][HTML] Influence of the microbiome, diet and genetics on inter-individual variation in the human plasma metabolome
The levels of the thousands of metabolites in the human plasma metabolome are strongly
influenced by an individual's genetics and the composition of their diet and gut microbiome …
influenced by an individual's genetics and the composition of their diet and gut microbiome …
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites
D Bogaert, GJ Van Beveren, EM de Koff, PL Parga… - Cell Host & Microbe, 2023 - cell.com
Early-life microbiota seeding and subsequent development is crucial to future health.
Cesarean-section (CS) birth, as opposed to vaginal delivery, affects early mother-to-infant …
Cesarean-section (CS) birth, as opposed to vaginal delivery, affects early mother-to-infant …
Cardiometabolic health, diet and the gut microbiome: A meta-omics perspective
Cardiometabolic diseases have become a leading cause of morbidity and mortality globally.
They have been tightly linked to microbiome taxonomic and functional composition, with diet …
They have been tightly linked to microbiome taxonomic and functional composition, with diet …
A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers
M Fidelle, C Rauber, C Alves Costa Silva, AL Tian… - Science, 2023 - science.org
Antibiotics (ABX) compromise the efficacy of programmed cell death protein 1 (PD-1)
blockade in cancer patients, but the mechanisms underlying their immunosuppressive …
blockade in cancer patients, but the mechanisms underlying their immunosuppressive …
[HTML][HTML] Insights into endogenous Bifidobacterium species in the human gut microbiota during adulthood
Bifidobacteria are among the earliest and most abundant bacterial colonizers of the
neonatal gut in many mammals, where they elicit purported host health benefits. While early …
neonatal gut in many mammals, where they elicit purported host health benefits. While early …
[HTML][HTML] Faecal microbiome-based machine learning for multi-class disease diagnosis
Systemic characterisation of the human faecal microbiome provides the opportunity to
develop non-invasive approaches in the diagnosis of a major human disease. However …
develop non-invasive approaches in the diagnosis of a major human disease. However …