Recent Trends in the development of novel metal-based antineoplastic drugs

L Todorov, I Kostova - Molecules, 2023 - mdpi.com
Since the accidental discovery of the anticancer properties of cisplatin more than half a
century ago, significant efforts by the broad scientific community have been and are currently …

Vibrational spectroscopic characterization and structural investigations of Cepharanthine, a natural alkaloid

S Celik, S Akyuz, AE Ozel - Journal of Molecular Structure, 2022 - Elsevier
Cepharanthine, a natural alkaloid obtained from the Stephania cepharantha Hayata plant,
that has antitumor, anti-inflammatory, antioxidative, antiparasitic, and antiviral properties …

A convergent multicomponent synthesis, spectral analysis, molecular modelling and docking studies of novel 2H-pyrido [1, 2-a] pyrimidine-2, 4 (3H)-dione derivatives …

N Afza, P Trivedi, A Bishnoi, S Parveen, S Kumar… - Journal of Molecular …, 2023 - Elsevier
A series of Novel hybrid 3, 3-dimethyl-13-(substituted-phenyl)-3, 4, 5, 13-tetrahydro-1H-
pyrido [1′, 2′: 1, 2] pyrimido [4, 5-b] quinoline-1, 12 (2H)-dione derivatives were designed …

In vitro anticancer activity of Pd (II) complexes with pyridine scaffold: Their bioactivity, role in cell cycle arrest, and computational study

R Bhaduri, A Pan, SK Tarai, S Mandal, A Bagchi… - Journal of Molecular …, 2022 - Elsevier
A series of Pd (II) based complexes [Pd (PEA) Cl 2]; Pd1,[Pd (PEA)(H 2 O) 2] 2+; Pd2,[Pd
(PEA)(DL-meth)] 2+; Pd3,[Pd (PEA)(DL-pen)]+; Pd4,[Pd (PEA)(OX)]; Pd5 and [Pd …

Structural and vibrational investigations and molecular docking studies of a vinca alkoloid, vinorelbine

S Celik, S Akyuz, AE Ozel - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Vinorelbine, a vinca alkaloid, is an antimitotic drug that inhibits polymerisation process of
tubulins to microtubules, and is widely used in cancer chemotherapy. Due to the importance …

Platinum-based cancer chemotherapeutics: Recent trends and future perspectives

S Parveen - Current Chinese Science, 2022 - ingentaconnect.com
Platinum-based drugs have been proved to be one of the prevalent successes in the field of
inorganic medicinal chemistry. So far, three generations of platinum-based drugs are on the …

Experimental and computational investigations on the molecular structure, vibrational spectra, electronic properties, and molecular electrostatic potential analysis of …

N Kaya Kınaytürk, T Kalaycı, B Tunalı - Spectroscopy Letters, 2021 - Taylor & Francis
Abstract The experimental Fourier Transform-Infrared, Raman, and Ultraviolet-Visible
spectral data along with the theoretical quantum chemical calculations for …

Experimental and theoretical investigations (FTIR, UV-VIS spectroscopy, HOMO-LUMO, NLO and MEP analysis) of aminothiophenol isomers

T Kalaycı, NK Kınaytürk, B Tunalı - Bulletin of the Chemical Society of …, 2021 - ajol.info
In this research, theoretical and experimental investigation was performed on the structural
and spectral data of aminothiophenol isomers. The theoretical electronic structure analyses …

From Molecules to Devices: Insights into Electronic and Optical Properties of Pyridine-Derived Compounds Using Density Functional Theory Calculations

A Mahmood, T Akram, S Chen… - The Journal of Physical …, 2024 - ACS Publications
In this study, we delve into the electronic structure, spectroscopic, and optical properties of
five benzo derivatives of pyridine, namely, 5-(4-chlorophenyl)-2-fluoropyridine (1), 2-fluoro-5 …

Palladium and platinum complexes based on pyridine bases induced anticancer effectiveness via apoptosis protein signaling in cancer cells

MM El-Bendary, A Akhdhar, AS Al-Bogami, D Domyati… - BioMetals, 2024 - Springer
Palladium and platinum complexes, especially those that include cisplatin, can be useful
chemotherapeutic drugs. Alternatives that have less adverse effects and require lower …