Rheumatoid arthritis (RA) is an autoimmune disease with an important inflammatory
component accompanied by deregulated redox-dependent signaling pathways that are …

Ethnopharmacological relevance Aconitum medicinal materials, such as Aconitum
carmichaelii Debeaux (Chinese: Wutou/乌头) and Aconitum kusnezoffii Reichb.(Chinese …

At the moment, anaplastic changes within the brain are challenging due to the complexity of
neural tissue, leading to the inefficiency of therapeutic protocols. The existence of a cellular …

Background Approximately 20% of all cancer patients will develop brain metastases in their
lifespan. The standard of care for patients with multiple brain metastases is whole-brain …

Peripheral contact to pathogen-associated molecular patterns (PAMPs) evokes a systemic
innate immune response which is rapidly relayed to the central nervous system (CNS). The …

P-glycoprotein (P-gp) is a crucial membrane transporter situated on the cell's apical surface,
being responsible for eliminating xenobiotics and endobiotics. P-gp modulators are …

Core clinical pharmacology principles must be considered when designing and executing
neonatal clinical trials. In this review, the authors discuss important aspects of drug dose …

Inflammatory bowel disease is a set of chronic inflammatory diseases that mainly develop in
the gastrointestinal mucosa, including ulcerative colitis and Crohn's disease …

Background: Limited evidence from case reports suggests that coronavirus disease 2019
(COVID-19) vaccination may interact with the treatment outcomes of psychiatric medications …

This study evaluates the influence of pregnancy and HIV infection in conjunction with the
use of raltegravir, lamivudine, and tenofovir disoproxil fumarate (combined antiretroviral …