Targeting vascular (endothelial) dysfunction
A Daiber, S Steven, A Weber… - British journal of …, 2017 - Wiley Online Library
Cardiovascular diseases are major contributors to global deaths and disability‐adjusted life
years, with hypertension a significant risk factor for all causes of death. The endothelium that …
years, with hypertension a significant risk factor for all causes of death. The endothelium that …
Physiological diagnostic criteria for vascular failure
A Tanaka, H Tomiyama, T Maruhashi, Y Matsuzawa… - …, 2018 - Am Heart Assoc
Briefly, measurement of flow-mediated vasodilation (FMD) of the brachial artery has been
used for the assessment of endothelial function in humans. 14, 15 This technique measures …
used for the assessment of endothelial function in humans. 14, 15 This technique measures …
Reference intervals for brachial artery flow-mediated dilation and the relation with cardiovascular risk factors
SM Holder, RM Bruno, DA Shkredova, EA Dawson… - …, 2021 - Am Heart Assoc
Endothelial function, assessed using brachial artery flow-mediated dilation (FMD), predicts
future cardiovascular disease (CVD) risk. This study established age-and sex-specific …
future cardiovascular disease (CVD) risk. This study established age-and sex-specific …
Pathophysiological association between diabetes mellitus and endothelial dysfunction
T Maruhashi, Y Higashi - Antioxidants, 2021 - mdpi.com
Endothelial dysfunction plays a critical role in atherosclerosis progression, leading to
cardiovascular complications. There are significant associations between diabetes mellitus …
cardiovascular complications. There are significant associations between diabetes mellitus …
Diagnostic criteria of flow‐mediated vasodilation for normal endothelial function and nitroglycerin‐induced vasodilation for normal vascular smooth muscle function of …
T Maruhashi, M Kajikawa, S Kishimoto… - Journal of the …, 2020 - Am Heart Assoc
Background Diagnostic criteria of flow‐mediated vasodilation (FMD), an index of endothelial
function, and nitroglycerin‐induced vasodilation (NID), an index of vascular smooth muscle …
function, and nitroglycerin‐induced vasodilation (NID), an index of vascular smooth muscle …
Endothelial dysfunction, increased arterial stiffness, and cardiovascular risk prediction in patients with coronary artery disease: FMD‐J (Flow‐Mediated Dilation Japan) …
T Maruhashi, J Soga, N Fujimura, N Idei… - Journal of the …, 2018 - Am Heart Assoc
Background The usefulness of vascular function tests for management of patients with a
history of coronary artery disease is not fully known. Methods and Results We measured …
history of coronary artery disease is not fully known. Methods and Results We measured …
Endothelial Function in dyslipidemia: roles of LDL-cholesterol, HDL-cholesterol and triglycerides
Y Higashi - Cells, 2023 - mdpi.com
Dyslipidemia is associated with endothelial dysfunction. Endothelial dysfunction is the initial
step for atherosclerosis, resulting in cardiovascular complications. It is clinically important to …
step for atherosclerosis, resulting in cardiovascular complications. It is clinically important to …
Atherothrombosis and oxidative stress: mechanisms and management in elderly
Significance: The incidence of cardiovascular events (CVEs) increases with age,
representing the main cause of death in an elderly population. Aging is associated with …
representing the main cause of death in an elderly population. Aging is associated with …
Clinical assessment of endothelial function in convalescent COVID-19 patients: a meta-analysis with meta-regressions
P Ambrosino, S Sanduzzi Zamparelli, M Mosella… - Annals of …, 2022 - Taylor & Francis
Background Endothelial dysfunction has been proposed to play a key role in the
pathogenesis of coronavirus disease 2019 (COVID-19) and its post-acute sequelae. Flow …
pathogenesis of coronavirus disease 2019 (COVID-19) and its post-acute sequelae. Flow …
DPP-4 inhibitor and alpha-glucosidase inhibitor equally improve endothelial function in patients with type 2 diabetes: EDGE study
K Nakamura, H Oe, H Kihara, K Shimada… - Cardiovascular …, 2014 - Springer
Background Alpha glucosidase inhibitor (GI) attenuates postprandial hyperglycemia (PPH)
and reduces the risk of cardiovascular events in patients with impaired glucose tolerance or …
and reduces the risk of cardiovascular events in patients with impaired glucose tolerance or …