Advances in biomaterial‐based spinal cord injury repair
H Shen, C Fan, Z You, Z Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …
challenge in neurological clinical practice. Understanding the pathophysiological changes …
[HTML][HTML] Stem cell-derived neuronal relay strategies and functional electrical stimulation for treatment of spinal cord injury
BQ Lai, X Zeng, WT Han, MT Che, Y Ding, G Li… - Biomaterials, 2021 - Elsevier
The inability of adult mammals to recover function lost after severe spinal cord injury (SCI)
has been known for millennia and is mainly attributed to a failure of brain-derived nerve fiber …
has been known for millennia and is mainly attributed to a failure of brain-derived nerve fiber …
Developing a mechanically matched decellularized spinal cord scaffold for the in situ matrix-based neural repair of spinal cord injury
Y Ma, H Shi, Q Wei, Q Deng, J Sun, Z Liu, B Lai, G Li… - Biomaterials, 2021 - Elsevier
Tissue engineering is a promising strategy to repair spinal cord injury (SCI). However, a
bioscaffold with mechanical properties that match those of the pathological spinal cord …
bioscaffold with mechanical properties that match those of the pathological spinal cord …
Polycaprolactone electrospun fiber scaffold loaded with iPSCs-NSCs and ASCs as a novel tissue engineering scaffold for the treatment of spinal cord injury
XH Zhou, GD Shi, BY Fan, X Cheng… - International journal …, 2018 - Taylor & Francis
Background Spinal cord injury (SCI) is a traumatic disease of the central nervous system,
accompanied with high incidence and high disability rate. Tissue engineering scaffold can …
accompanied with high incidence and high disability rate. Tissue engineering scaffold can …
Advances in 3D bioprinting for neural tissue engineering
Current therapies for nerve regeneration within injured tissues have had limited success due
to complicated neural anatomy and inhibitory barriers in situ. Recent advancements in 3D …
to complicated neural anatomy and inhibitory barriers in situ. Recent advancements in 3D …
[HTML][HTML] Tissue-engineered regeneration of completely transected spinal cord using induced neural stem cells and gelatin-electrospun poly (lactide-co-glycolide) …
C Liu, Y Huang, M Pang, Y Yang, S Li, L Liu, T Shu… - PloS one, 2015 - journals.plos.org
Tissue engineering has brought new possibilities for the treatment of spinal cord injury. Two
important components for tissue engineering of the spinal cord include a suitable cell source …
important components for tissue engineering of the spinal cord include a suitable cell source …
Spinal cord injury repair by implantation of structured hyaluronic acid scaffold with PLGA microspheres in the rat
Y Wen, S Yu, Y Wu, R Ju, H Wang, Y Liu… - Cell and Tissue …, 2016 - Springer
In order to create an optimal microenvironment for neural regeneration in the lesion area
after spinal cord injury (SCI), we fabricated a novel scaffold composed of a hyaluronic acid …
after spinal cord injury (SCI), we fabricated a novel scaffold composed of a hyaluronic acid …
Transplantation of tissue engineering neural network and formation of neuronal relay into the transected rat spinal cord
BQ Lai, MT Che, BL Du, X Zeng, YH Ma, B Feng… - Biomaterials, 2016 - Elsevier
Severe spinal cord injury (SCI) causes loss of neural connectivity and permanent functional
deficits. Re-establishment of new neuronal relay circuits after SCI is therefore of paramount …
deficits. Re-establishment of new neuronal relay circuits after SCI is therefore of paramount …
[HTML][HTML] Complete rat spinal cord transection as a faithful model of spinal cord injury for translational cell transplantation
D Lukovic, V Moreno-Manzano, E Lopez-Mocholi… - Scientific reports, 2015 - nature.com
Spinal cord injury (SCI) results in neural loss and consequently motor and sensory
impairment below the injury. There are currently no effective therapies for the treatment of …
impairment below the injury. There are currently no effective therapies for the treatment of …
A modular assembly of spinal cord–like tissue allows targeted tissue repair in the transected spinal cord
BQ Lai, B Feng, MT Che, LJ Wang, S Cai… - Advanced …, 2018 - Wiley Online Library
Tissue engineering–based neural construction holds promise in providing organoids with
defined differentiation and therapeutic potentials. Here, a bioengineered transplantable …
defined differentiation and therapeutic potentials. Here, a bioengineered transplantable …