The oxytocin receptor: from intracellular signaling to behavior
B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …
Intranasal oxytocin: myths and delusions
G Leng, M Ludwig - Biological psychiatry, 2016 - Elsevier
Despite widespread reports that intranasal application of oxytocin has a variety of behavioral
effects, very little of the huge amounts applied intranasally appears to reach the …
effects, very little of the huge amounts applied intranasally appears to reach the …
[HTML][HTML] Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques
MR Lee, TA Shnitko, SW Blue, AV Kaucher… - Nature …, 2020 - nature.com
Oxytocin may have promise as a treatment for neuropsychiatric disorders. Its therapeutic
effect may depend on its ability to enter the brain and bind to the oxytocin receptor. To date …
effect may depend on its ability to enter the brain and bind to the oxytocin receptor. To date …
Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity
Background Current neuroimaging perspectives on a variety of mental disorders emphasize
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …
Oxytocin by intranasal and intravenous routes reaches the cerebrospinal fluid in rhesus macaques: determination using a novel oxytocin assay
MR Lee, KB Scheidweiler, XX Diao, F Akhlaghi… - Molecular …, 2018 - nature.com
Oxytocin (OT) is a potential treatment for multiple neuropsychiatric disorders. As OT is a
peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies …
peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies …
Does oxytocin increase trust in humans? A critical review of research
Behavioral neuroscientists have shown that the neuropeptide oxytocin (OT) plays a key role
in social attachment and affiliation in nonhuman mammals. Inspired by this initial research …
in social attachment and affiliation in nonhuman mammals. Inspired by this initial research …
[HTML][HTML] Oxytocin and vasopressin: linking pituitary neuropeptides and their receptors to social neurocircuits
DA Baribeau, E Anagnostou - Frontiers in neuroscience, 2015 - frontiersin.org
Oxytocin and vasopressin are pituitary neuropeptides that have been shown to affect social
processes in mammals. There is growing interest in these molecules and their receptors as …
processes in mammals. There is growing interest in these molecules and their receptors as …
[HTML][HTML] Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice
Y Yamamoto, M Liang, S Munesue, K Deguchi… - Communications …, 2019 - nature.com
Oxytocin sets the stage for childbirth by initiating uterine contractions, lactation and maternal
bonding behaviours. Mice lacking secreted oxcytocin (Oxt−/−, Cd38−/−) or its receptor …
bonding behaviours. Mice lacking secreted oxcytocin (Oxt−/−, Cd38−/−) or its receptor …
[HTML][HTML] Nose-to-brain delivery of therapeutic peptides as nasal aerosols
Central nervous system (CNS) disorders, such as psychiatric disorders, neurodegeneration,
chronic pain, stroke, brain tumor, spinal cord injury, and many other CNS diseases, would …
chronic pain, stroke, brain tumor, spinal cord injury, and many other CNS diseases, would …
[HTML][HTML] The effects of oxytocin on appetite regulation, food intake and metabolism in humans
L Kerem, EA Lawson - International Journal of Molecular Sciences, 2021 - mdpi.com
The hypothalamic peptide oxytocin and its receptor are involved in a range of physiological
processes, including parturition, lactation, cell growth, wound healing, and social behavior …
processes, including parturition, lactation, cell growth, wound healing, and social behavior …