Inside individual cells, protein population counts are subject to molecular noise due to low
copy numbers and the inherent probabilistic nature of biochemical processes. We …

Gene-expression bimodality, as a potential mechanism generating phenotypic cell diversity,
can enhance the survival of cells in a fluctuating environment. Previous studies have shown …

Many cellular events occur when their corresponding regulatory proteins attain critical
thresholds. Can cells schedule such events with precision by controlling the dynamics of the …

The timing of cellular events is often determined by the instant when the level of a chemical
species crosses a threshold from an initial value of zero. To attenuate the inherent random …

The timing of biochemical events is often determined by the accumulation of a protein or
chemical species to a critical threshold level. In a stochastic model, we define event timing …

The timing of diverse cellular processes is based on the instant when the concentration of
regulatory proteins crosses a critical threshold level. Hence, noise mechanisms inherent to …

The timing of diverse cellular processes is based on the instant when the concentration of
regulatory proteins crosses a critical threshold level. Hence, noise mechanisms inherent to …

Gene expression is inherently a stochastic process, leading to randomness in the timing of
events. A problem of interest is to understand how cells achieve temporal precision …

The timing of biochemical processes within cells is inextricably linked to the level of key
regulatory proteins crossing critical threshold levels. Recent research has primarily focused …

Cellular response to a stimulus is often triggered by accumulation of an appropriate gene
product up to a critical threshold. How cells regulate gene expression to achieve precision in …