RNA helicases of the DEAD‐box and related families have been found to be required for all
processes involving RNA molecules. Biochemical and genetic analyses have shown that at …

The translation, localization, and degradation of cytoplasmic mRNAs are controlled by the
formation and rearrangement of their mRNPs. The conserved Ded1/DDX3 DEAD-box …

The present invention provides compositions for RNA interference and methods of use
thereof. In particular, the invention provides single-stranded small interfering RNAs …

DEAD-box RNA helicases, which are involved in virtually all aspects of RNA metabolism,
are generally viewed as enzymes that unwind RNA duplexes or disrupt RNA− protein …

Recent results suggest that cytoplasmic mRNAs can form translationally repressed
messenger ribonucleoprotein particles (mRNPs) capable of decapping and degradation, or …

Phenazines produced by Pseudomonas and Streptomyces spp. are heterocyclic nitrogen-
containing metabolites with antibiotic, antitumor, and antiparasitic activity. The antibiotic …

Many fungal genomes have now been sequenced and thousands of genes are being
discovered. Gene disruption or inactivation technology offers an important tool not only for …

Double‐stranded RNA (dsRNA) can specifically inhibit gene expression in a variety of
organisms by invoking post‐transcriptional degradation of homologous mRNA. Here we …

DEAD-box helicase proteins accelerate folding and rearrangements of highly structured
RNAs and RNA–protein complexes (RNPs) in many essential cellular processes. Although …

Fission yeast, Schizoaccharomyces pombe, is a model for studying cellular quiescence.
Shifting to a medium that lacks a nitrogen-source induces proliferative cells to enter long …