Cytokine networks dysregulation during HTLV-1 infection and associated diseases

N Futsch, G Prates, R Mahieux, J Casseb, H Dutartre - Viruses, 2018 - mdpi.com
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a neural chronic
inflammation, called HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …

Impact of host immunity on HTLV-1 pathogenesis: potential of Tax-targeted immunotherapy against ATL

M Kannagi, A Hasegawa, Y Nagano, S Kimpara… - Retrovirology, 2019 - Springer
Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL),
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other …

Interplay between innate immunity and the viral oncoproteins Tax and HBZ in the pathogenesis and therapeutic response of HTLV-1 associated adult T cell leukemia

H El Hajj, A Bazarbachi - Frontiers in Immunology, 2022 - frontiersin.org
The Human T-cell Leukemia virus type 1 (HTLV-1) causes an array of pathologies, the most
aggressive of which is adult T-cell leukemia (ATL), a fatal blood malignancy with dismal …

Following the clues: usefulness of biomarkers of neuroinflammation and neurodegeneration in the investigation of HTLV-1-associated myelopathy progression

FS Souza, NL Freitas, YCP Gomes, RC Torres… - Frontiers in …, 2021 - frontiersin.org
Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a neurodegenerative disease due to axonal damage of the …

Differential modulation of IL-4, IL-10, IL-17, and IFN-γ production mediated by IgG from Human T-lymphotropic virus-1 (HTLV-1) infected patients on healthy peripheral …

NR Machado, BO Fagundes, LA Fernandes… - Frontiers in …, 2023 - frontiersin.org
Human T-lymphotropic virus 1 (HTLV-1) infected individuals remain as asymptomatic
carriers (ACs) or can develop the chronic neurological disorder HTLV-1-associated …

Human T lymphotropic virus 1-associated myelopathy: overview of human T cell lymphotropic virus-1/2 tests and potential biomarkers

M Puccioni-Sohler, AR Poton… - AIDS Research and …, 2022 - liebertpub.com
Human T cell lymphotropic virus (HTLV)-1-associated myelopathy is a chronic, disabling
inflammatory disorder of the spinal cord caused by HTLV-1 infection. The diagnosis of HTLV …

Novel insights into human T‐lymphotropic virus type‐1 (HTLV‐1) pathogenesis‐host interactions in the manifestation of HTLV‐1‐associated myelopathy/tropical …

S Ahmadi Ghezeldasht, A Mosavat… - Reviews in Medical …, 2024 - Wiley Online Library
Human T‐lymphotropic virus type‐1 (HTLV‐1) was the first discovered human oncogenic
retrovirus, the etiological agent of two serious diseases have been identified as adult T‐cell …

Unveiling the anti-senescence effects and senescence-associated secretory phenotype (SASP) inhibitory mechanisms of Scutellaria baicalensis Georgi in low …

L Gao, W Yang, H Qi, CJ Sun, X Qin, G Du - Phytomedicine, 2022 - Elsevier
Background Astrocytes senescence has been demonstrated in the aging brain and
Alzheimer's disease (AD). Moreover, lower glucose metabolism has been confirmed in the …

Hypovitaminosis D is associated with higher levels of inflammatory cytokines and with HAM/TSP in HTLV-Infected patients

EC Netto, AC Silva, C Pedroso, C Brites - Viruses, 2021 - mdpi.com
Recent studies have shown the effects of vitamin D on host response to infectious diseases.
Some studies detected a high prevalence of hypovitaminosis D in HIV-infected patients, but …

Influence of immunogenetic biomarkers in the clinical outcome of HTLV-1 infected persons

ACR Vallinoto, I Cayres-Vallinoto, MA Freitas Queiroz… - Viruses, 2019 - mdpi.com
Human T-lymphotropic virus 1, a member of the Retroviridae family, causes a neglected,
silent, persistent infection affecting circa 5 to 10 million people around the world, with …