Potential roles of m6A and FTO in synaptic connectivity and major depressive disorder

H Mitsuhashi, C Nagy - International journal of molecular sciences, 2023 - mdpi.com
RNA modifications known as epitranscriptomics have emerged as a novel layer of
transcriptomic regulation. Like the well-studied epigenetic modifications characterized in …

Ribonucleic acid-mediated control of protein translation under stress

MJ Payea, SA Dar, S Malla… - Antioxidants & Redox …, 2023 - liebertpub.com
Significance: The need of cells to constantly respond to endogenous and exogenous stress
has necessitated the evolution of pathways to counter the deleterious effects of stress and to …

An Exploration of the Coherent Effects between METTL3 and NDUFA10 on Alzheimer's Disease

L Yang, X Pang, W Guo, C Zhu, L Yu, X Song… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized primarily by a
decline in cognitive function. However, the etiopathogenesis of AD is unclear. N6 …

Influence of metabolic, transporter, and pathogenic genes on pharmacogenetics and DNA methylation in neurological disorders

O Martínez-Iglesias, V Naidoo, I Carrera, JC Carril… - Biology, 2023 - mdpi.com
Simple Summary The prevalence of neurodegenerative disorders has increased, yet
reliable, pre-symptomatic biomarkers for early detection and subsequent preventive …

Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA

R Zhang, Y Zhang, F Guo, G Huang, Y Zhao… - Cell Death …, 2022 - nature.com
Abstract N6-methyladenosine (m6A) is abundant in the mammalian brain and is considered
to have a wide range of effects on learning and memory. Here, we found that the …

Regulatory roles of N6-methyladenosine (m6A) methylation in RNA processing and non-communicable diseases

FA Khan, B Nsengimana, UA Awan, XY Ji, S Ji… - Cancer Gene …, 2024 - nature.com
Post-transcriptional RNA modification is an emerging epigenetic control mechanism in cells
that is important in many different cellular and organismal processes. N6-methyladenosine …

An update on preclinical research in anesthetic-induced developmental neurotoxicity in nonhuman primate and rodent models

V Neudecker, J Xu, MA Thomas… - Journal of …, 2023 - journals.lww.com
The 2022 Pediatric Anesthesia and NeuroDevelopment Assessment (PANDA) Meeting
included an update on preclinical research in the field of anesthetic-induced developmental …

[PDF][PDF] Involvement of nucleic-acid methylation on biology and evolution: from first hominids to modern humans–Review

G Dorado, F Luque, FJ Esteban, P Pascual… - …, 2022 - researchgate.net
Recent developments in molecular biology, in general, and nucleic-acid sequencing, in
particular, have allowed fascinating discoveries. Thus, it is now known that DNA and RNA …

Dynamics of N6-methyladenosine modification during Alzheimer's disease development

S Gao, Y Wang, X Li, Y Liang, Z Jin, B Yang, TF Yuan… - Heliyon, 2024 - cell.com
Abstract N6-methyladenosine (m6A) modification is a common RNA modification in the
central nervous system and has been linked to various neurological disorders, including …

Implicación de la metilación de ácidos nucleicos en biología y evolución: desde los primeros homínidos hasta los humanos modernos: Revisión

G Dorado, F Luque, FJ Esteban, P Pascual… - …, 2022 - dialnet.unirioja.es
Los avances recientes en biología molecular, en general, y secuenciación de ácidos
nucleicos, en particular, han posibilitado descubrimientos fascinantes. Así, ahora se sabe …