Impact of bilayer lipid composition on the structure and topology of the transmembrane amyloid precursor C99 protein

Y Song, KF Mittendorf, Z Lu… - Journal of the American …, 2014 - ACS Publications
C99 (also known as β-CTF) is the 99 residue transmembrane C-terminal domain (residues
672–770) of the amyloid precursor protein and is the immediate precursor of the amyloid-β …

Orientation and order of the amide group of sphingomyelin in bilayers determined by solid-state NMR

N Matsumori, T Yamaguchi, Y Maeta, M Murata - Biophysical Journal, 2015 - cell.com
Sphingomyelin (SM) and cholesterol (Chol) are considered essential for the formation of
lipid rafts; however, the types of molecular interactions involved in this process, such as …

NMR spin-couplings in saccharides: Relationships between structure, conformation and the magnitudes of JHH, JCH and JCC values

MJ Hadad, W Zhang, T Turney, L Sernau, X Wang… - 2017 - books.rsc.org
2.1 Introduction and Background the nMr spin–spin coupling constant (spin–spin coupling,
spin-coupling, scalar coupling, or J-coupling) plays a pivotal role in modern liquid-phase …

Analytical methods in sphingolipidomics: Quantitative and profiling approaches in food analysis

N Canela, P Herrero, S Mariné, P Nadal… - … of Chromatography A, 2016 - Elsevier
In recent years, sphingolipidomics has emerged as an interesting omic science that
encompasses the study of the full sphingolipidome characterization, content, structure and …

Bioactive structure of membrane lipids and natural products elucidated by a chemistry‐based approach

M Murata, S Sugiyama, S Matsuoka… - The Chemical …, 2015 - Wiley Online Library
Determining the bioactive structure of membrane lipids is a new concept, which aims to
examine the functions of lipids with respect to their three‐dimensional structures. As lipids …

Theonellamide A, a marine-sponge-derived bicyclic peptide, binds to cholesterol in aqueous DMSO: Solution NMR-based analysis of peptide-sterol interactions using …

K Cornelio, RA Espiritu, S Hanashima… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Theonellamides (TNMs) are antifungal and cytotoxic bicyclic dodecapeptides isolated from
the marine sponge Theonella sp. The inclusion of cholesterol (Chol) or ergosterol in the …

Evaluation of molecular ordering in bicelle bilayer membranes based on induced circular dichroism spectra

K Suga, K Kitagawa, S Taguchi, Y Okamoto… - Langmuir, 2020 - ACS Publications
Bicelles are submicrometer-sized disc-shaped molecular self-assemblies that can be
obtained in aqueous solution by dispersing mixtures of certain amphiphiles. Although …

Combination of roll grinding and high-pressure homogenization can prepare stable bicelles for drug delivery

S Matsuo, K Higashi, K Moribe, S Kimura, S Itai… - Nanomaterials, 2018 - mdpi.com
To improve the solubility of the drug nifedipine (NI), NI-encapsulated lipid-based
nanoparticles (NI-LNs) have been prepared from neutral hydrogenated soybean …

[HTML][HTML] The application of open disk-like structures as model membrane and drug carriers

W Zhang, J Sun, Z He - asian journal of pharmaceutical sciences, 2013 - Elsevier
The objective of this review is to outline the application of bicelles (or called bilayer micelles)
and bilayer nanodisks in pharmaceutics, pharmaceutical analysis and biochemistry. The …

Tailoring bicelle morphology and thermal stability with lanthanide-chelating cholesterol conjugates

S Isabettini, M Liebi, J Kohlbrecher, T Ishikawa… - Langmuir, 2016 - ACS Publications
Bicelles composed of DMPC and phospholipids capable of chelating lanthanide ions, such
as 1, 2-dimyristoyl-sn-glycero-3-phospho-ethanolamine-diethylene triaminepentaacetate …