Quantitative NMR-based biomedical metabolomics: Current status and applications

AA Crook, R Powers - Molecules, 2020 - mdpi.com
Nuclear Magnetic Resonance (NMR) spectroscopy is a quantitative analytical tool
commonly utilized for metabolomics analysis. Quantitative NMR (qNMR) is a field of NMR …

Recent advances in NMR-based metabolomics

GA Nagana Gowda, D Raftery - Analytical Chemistry, 2017 - ACS Publications
NMR spectroscopy, one of the two major analytical platforms utilized in the metabolomics
field, has witnessed a large number of advances in fundamental studies, methods …

Diagnosis of major depressive disorder based on changes in multiple plasma neurotransmitters: a targeted metabolomics study

JX Pan, JJ Xia, FL Deng, WW Liang, J Wu… - Translational …, 2018 - nature.com
Major depressive disorder (MDD) is a debilitating psychiatric illness. However, there is
currently no objective laboratory-based diagnostic tests for this disorder. Although …

Efficacy of ketamine in the rapid treatment of major depressive disorder: a meta-analysis of randomized, double-blind, placebo-controlled studies

Y Han, J Chen, D Zou, P Zheng, Q Li… - Neuropsychiatric …, 2016 - Taylor & Francis
Background An increasing number of studies are reporting that ketamine could be treated as
a novel antidepressant for major depressive disorder (MDD). Therefore, we performed this …

Urinary biomarkers of brain diseases

M An, Y Gao - Genomics, Proteomics and Bioinformatics, 2015 - academic.oup.com
Biomarkers are the measurable changes associated with a physiological or
pathophysiological process. Unlike blood, urine is not subject to homeostatic mechanisms …

Comparative efficacy and acceptability of electroconvulsive therapy versus repetitive transcranial magnetic stimulation for major depression: a systematic review and …

J Chen, L Zhao, Y Liu, S Fan, P Xie - Behavioural Brain Research, 2017 - Elsevier
Backgrounds The effects of electroconvulsive therapy (ECT) and bilateral, left prefrontal, and
right prefrontal repetitive transcranial magnetic stimulation (rTMS) on major depressive …

Metabolomics and lipidomics of ischemic stroke

A Au - Advances in clinical chemistry, 2018 - Elsevier
Ischemic stroke is a sudden loss of brain function due to the reduction of blood flow. Brain
tissues cease to function with subsequent activation of the ischemic cascade. Metabolomics …

Comparison of the proximate composition, vitamins (ascorbic acid, α-tocopherol and retinol), anti-nutrients (phytate and oxalate) and the GC-MS analysis of the …

OA Idris, OA Wintola, AJ Afolayan - Plants, 2019 - mdpi.com
Medicinal plants are a pertinent and effective remedy, employed in indigenous healthcare
systems by traditional healers. This study focused on proximate parameters, minerals …

Urinary biomarker panel for diagnosing patients with depression and anxiety disorders

J Chen, SJ Bai, W Li, C Zhou, P Zheng, L Fang… - Translational …, 2018 - nature.com
Available data indicate that patients with depression and anxiety disorders are likely to be at
greater risk for suicide. Therefore, it is important to correctly diagnose patients with …

Metabolite identification in fecal microbiota transplantation mouse livers and combined proteomics with chronic unpredictive mild stress mouse livers

B Li, K Guo, L Zeng, B Zeng, R Huo, Y Luo… - Translational …, 2018 - nature.com
Major depressive disorder (MDD) is a common mood disorder. Gut microbiota may be
involved in the pathogenesis of depression via the microbe–gut–brain axis. Liver is …