Simple Summary The myogenic differentiation 1 gene (MYOD1) p. L122R mutation was first
discovered in a subset of clinically aggressive rhabdomyosarcomas in both adults and …

Soft tissue sarcomas (STS) represent a heterogeneous group of extraskeletal mesenchymal
tumors that affect individuals throughout the entire age continuum. Despite this pervasive …

Background Patients with alveolar rhabdomyosarcoma (ARMS) have inferior outcomes
compared to patients with embryonal rhabdomyosarcoma (ERMS) and more effective …

Importance Determining the impact of germline cancer-predisposition variants (CPVs) on
outcomes could inform novel approaches to testing and treating children with …

Simple Summary Patients with a metastatic rhabdomyosarcoma treated with a long-term
maintenance therapy (LTMT) as a final additional treatment element show a similar outcome …

Background Relative to other pediatric cancers, survival for rhabdomyosarcoma (RMS) has
not improved in recent decades, suggesting the need to enhance risk stratification …

Simple Summary Due to their rarity, we still know comparatively little about
rhabdomyosarcomas (RMS) in adolescents and young adults (AYA). Factors responsible for …

Background Temsirolimus has shown in vivo activity against rhabdomyosarcoma (RMS). We
aimed to determine the feasibility of incorporating temsirolimus within the standard …

Rhabdomyosarcoma frequently affects the craniofacial region with a rapid growing pattern
that usually results in swelling of the interested area. The present paper describes a peculiar …

Introduction The impact of established prognostic factors on survival outcomes for childhood
rhabdomyosarcoma (RMS) have not been well described in the adolescent and young adult …