Research progress of Lycium barbarum L. as functional food: phytochemical composition and health benefits

RH Ma, XX Zhang, K Thakur, JG Zhang… - Current Opinion in Food …, 2022 - Elsevier
Highlights•Lycium genus is rich in different compounds with a variety of biological
activities.•L. barbarum derived foods can be classified as dietary supplement or …

[HTML][HTML] Research progress in traditional Chinese medicine in the treatment of Alzheimer's disease and related dementias

W Tan, L Qi, X Hu, Z Tan - Frontiers in Pharmacology, 2022 - frontiersin.org
Alzheimer's disease (AD) is the world's leading cause of dementia and has become a huge
economic burden on nations and families. However, the exact etiology of AD is still …

[HTML][HTML] Defensing against oxidative stress in Caenorhabditis elegans of a polysaccharide LFP-05S from Lycii fructus

F Zhang, X Zhang, X Liang, K Wu, Y Cao, T Ma… - Carbohydrate …, 2022 - Elsevier
Oxidative stress is closely associated with the initiation and progression of aging.
Considerable interest centers in the potential application of natural polysaccharides in …

[HTML][HTML] Lycium barbarum glycopetide prolong lifespan and alleviate Parkinson's disease in Caenorhabditis elegans

J Zheng, Z Luo, K Chiu, Y Li, J Yang… - Frontiers in aging …, 2023 - ncbi.nlm.nih.gov
Methods The lifespan and body movement of C. elegans were used to evaluate the effect of
LbGp on lifespan and health span. The thrashing assay was used to determine the role of …

Therapeutic targeting of mitochondria–proteostasis axis by antioxidant polysaccharides in neurodegeneration

Q Wang, MZ Adil, X Xie, S Zhao, J Zhang… - Advances in Protein …, 2023 - Elsevier
Aging is a major risk factor for many age-associated disorders, including neurodegenerative
diseases. Both mitochondrial dysfunction and proteostatic decline are well-recognized …

Two new lignans with their biological activities in Portulaca oleracea L.

C Wang, S Guo, J Tian, P Liu, M Song, W Zhang… - Phytochemistry …, 2022 - Elsevier
Two new lignans, identified as 6, 7-dihydroxy-4-(4′'-hydroxy-3′'-methoxyphenyl)-2-
naphthoic acid, named Oleralignan C (1), and 4-(3, 4-dihydroxyphenyl)-6-hydroxy-7 …

Responses of bitter melon saponins to oxidative stress and aging via the IIS pathway linked with sir‐2.1 and hlh‐30

J Zhang, L He, A Wang, B Wu, P Zhang… - Journal of Food …, 2022 - Wiley Online Library
Saponins from bitter melon (BMS) exert potential bioactivities and pharmacological
activities, including anti‐oxidation and lifespan extension. However, the exact mechanisms …

[HTML][HTML] Metabolic Regulations of Smilax china L. against β-Amyloid Toxicity in Caenorhabditis elegans

L Yan, Y Deng, Y Du, X Fang, X Fang, Q Zhang - Metabolites, 2024 - mdpi.com
Smilax china L.(Chinaroot) is a natural herb that has multiple uses, such as being used to
make tea and food. Both its roots and leaves have different uses due to their unique …

[HTML][HTML] Evolutionary conserved peptide and glycoprotein hormone-like neuroendocrine systems in C. elegans

MN Istiban, N De Fruyt, S Kenis, I Beets - Molecular and Cellular …, 2024 - Elsevier
Peptides and protein hormones form the largest group of secreted signals that mediate
intercellular communication and are central regulators of physiology and behavior in all …

Anti-Aging of the Nervous System and Related Neurodegenerative Diseases With Chinese Herbal Medicine

X Du, N Lou, S Hu, R Xiao, C Chu… - American Journal of …, 2023 - journals.sagepub.com
Human beings have always pursued a prolonged lifespan, while the aging of the nervous
system is associated with a large variety of diseases. Pathological aging of the nervous …