[HTML][HTML] Effects of the TLR4/Myd88/NF-κB signaling pathway on NLRP3 inflammasome in coronary microembolization-induced myocardial injury
Q Su, L Li, Y Sun, H Yang, Z Ye, J Zhao - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Coronary microembolization (CME) is a common complication of acute
coronary syndrome (ACS) and percutaneous coronary intervention (PCI); Myocardial …
coronary syndrome (ACS) and percutaneous coronary intervention (PCI); Myocardial …
Nicorandil alleviates apoptosis in diabetic cardiomyopathy through PI3K/Akt pathway
X Wang, J Pan, D Liu, M Zhang, X Li… - Journal of Cellular …, 2019 - Wiley Online Library
Nicorandil exerts myocardial protection through its antihypoxia and antioxidant effects. Here,
we investigated whether it plays an anti‐apoptotic role in diabetic cardiomyopathy. Sprague …
we investigated whether it plays an anti‐apoptotic role in diabetic cardiomyopathy. Sprague …
Resveratrol attenuates cardiomyocyte apoptosis in rats induced by coronary microembolization through SIRT1-mediated deacetylation of p53
Q Mao, X Liang, Y Wu, Y Lu - Journal of cardiovascular …, 2019 - journals.sagepub.com
Objective: Coronary microembolization (CME)-induced cardiomyocyte apoptosis is the
primary factor in causing cardiac dysfunction. Resveratrol (RES) is known to play a …
primary factor in causing cardiac dysfunction. Resveratrol (RES) is known to play a …
[HTML][HTML] Therapeutic potential of nicorandil beyond anti-anginal drug: A review on current and future perspectives
D Singh, R Singh, AJ Akindele - Heliyon, 2024 - cell.com
Nicorandil (NIC) is a well-known anti-anginal agent, which has been recommended as one
of the second-line treatments for chronic stable angina as justified by the European …
of the second-line treatments for chronic stable angina as justified by the European …
Breviscapine pretreatment inhibits myocardial inflammation and apoptosis in rats after coronary microembolization by activating the PI3K/Akt/GSK-3β signaling …
ZQ Chen, Y Zhou, F Chen, JW Huang… - Drug design …, 2021 - Taylor & Francis
Purpose Coronary microembolization (CME) can cause myocardial inflammation, apoptosis
and progressive cardiac dysfunction. On the other hand, breviscapine exerts a significant …
and progressive cardiac dysfunction. On the other hand, breviscapine exerts a significant …
Nicorandil attenuates cisplatin-induced acute kidney injury in rats via activation of PI3K/AKT/mTOR signaling cascade and inhibition of autophagy
Cisplatin is a highly effective antitumor agent, but its clinical use is limited due to critical
adverse reactions including acute kidney injury (AKI). Nicorandil is an approved antianginal …
adverse reactions including acute kidney injury (AKI). Nicorandil is an approved antianginal …
Ligustrazine attenuates myocardial injury induced by coronary microembolization in rats by activating the PI3K/Akt pathway
Q Su, X Lv, Z Ye - Oxidative Medicine and Cellular Longevity, 2019 - Wiley Online Library
Background/Aims. Coronary microembolization‐(CME‐) induced myocardial injury and
progressive cardiac dysfunction are mainly caused due to CME‐induced myocardial local …
progressive cardiac dysfunction are mainly caused due to CME‐induced myocardial local …
Effects of nicorandil on QT prolongation and myocardial damage caused by citalopram in rats
G Akturk, SC Micili, O Gursoy Doruk… - Biotechnic & …, 2023 - Taylor & Francis
Citalopram is a selective serotonin re-uptake inhibitor (SSRI) antidepressant; it exhibits the
greatest cardiotoxic effect among SSRIs. Citalopram can cause drug-induced long QT …
greatest cardiotoxic effect among SSRIs. Citalopram can cause drug-induced long QT …
Nobiletin protects against myocardial injury and myocardial apoptosis following coronary microembolization via activating PI3K/Akt pathway in rats
Q Mao, X Liang, Y Wu, Y Lu - Naunyn-Schmiedeberg's Archives of …, 2019 - Springer
It has been found that use of drugs which upregulate the PI3K/Akt pathway can effectively
reduce cardiomyocyte apoptosis which has been induced by coronary microembolization …
reduce cardiomyocyte apoptosis which has been induced by coronary microembolization …
Anti-apoptotic effect of MiR-223-3p Suppressing PIK3C2A in cardiomyocytes from myocardial infarction rat through regulating PI3K/Akt signaling pathway
L Xiaoyu, Z Wei, Z Ming, J Guowei - Cardiovascular Toxicology, 2021 - Springer
We aimed to explore the regulatory mechanism of the axis of miR-223-3p-PIK3C2A-PI3K/Akt
on cardiomyocyte apoptosis in rats with myocardial infarction. Thirty 8-week-old healthy …
on cardiomyocyte apoptosis in rats with myocardial infarction. Thirty 8-week-old healthy …