Strategies to prevent sarcopenia in the aging process: Role of protein intake and exercise
PS Rogeri, R Zanella Jr, GL Martins, MDA Garcia… - Nutrients, 2021 - mdpi.com
Sarcopenia is one of the main issues associated with the process of aging. Characterized by
muscle mass loss, it is triggered by several conditions, including sedentary habits and …
muscle mass loss, it is triggered by several conditions, including sedentary habits and …
[HTML][HTML] Nutritional considerations for healthy aging and reduction in age-related chronic disease
A projected doubling in the global population of people aged≥ 60 y by the year 2050 has
major health and economic implications, especially in developing regions. Burdens of …
major health and economic implications, especially in developing regions. Burdens of …
Role and potential mechanisms of anabolic resistance in sarcopenia
PH Haran, DA Rivas, RA Fielding - Journal of cachexia, sarcopenia and …, 2012 - Springer
There is pressing need to understand the aging process to better cope with its associated
physical and societal costs. The age-related muscle wasting known as sarcopenia is a major …
physical and societal costs. The age-related muscle wasting known as sarcopenia is a major …
[HTML][HTML] Interaction of fibromodulin and myostatin to regulate skeletal muscle aging: an opposite regulation in muscle aging, diabetes, and intracellular lipid …
The objective of this study was to investigate fibromodulin (FMOD) and myostatin (MSTN)
gene expressions during skeletal muscle aging and to understand their involvements in this …
gene expressions during skeletal muscle aging and to understand their involvements in this …
Diminished anabolic signaling response to insulin induced by intramuscular lipid accumulation is associated with inflammation in aging but not obesity
DA Rivas, DJ McDonald, NP Rice… - American Journal …, 2016 - journals.physiology.org
The loss of skeletal muscle mass is observed in many pathophysiological conditions,
including aging and obesity. The loss of muscle mass and function with aging is defined as …
including aging and obesity. The loss of muscle mass and function with aging is defined as …
Increased ceramide content and NFκB signaling may contribute to the attenuation of anabolic signaling after resistance exercise in aged males
DA Rivas, EP Morris, PH Haran… - Journal of applied …, 2012 - journals.physiology.org
One of the most fundamental adaptive physiological events is the response of skeletal
muscle to high-intensity resistance exercise, resulting in increased protein synthesis and …
muscle to high-intensity resistance exercise, resulting in increased protein synthesis and …
A persistent level of Cisd2 extends healthy lifespan and delays aging in mice
CY Wu, YF Chen, CH Wang, CH Kao… - Human molecular …, 2012 - academic.oup.com
The CISD2 gene, which is an evolutionarily conserved novel gene, encodes a
transmembrane protein primarily associated with the mitochondrial outer membrane …
transmembrane protein primarily associated with the mitochondrial outer membrane …
miR-19b-3p is associated with a diametric response to resistance exercise in older adults and regulates skeletal muscle anabolism via PTEN inhibition
DA Rivas, F Peng, T Benard… - … of Physiology-Cell …, 2021 - journals.physiology.org
Understanding paradoxical responses to anabolic stimulation and identifying the
mechanisms for this inconsistency in mobility-limited older adults may provide new targets …
mechanisms for this inconsistency in mobility-limited older adults may provide new targets …
Inflammation and metabolism: the role of adiposity in sarcopenic obesity
GM Lynch, CH Murphy, E de Marco Castro… - Proceedings of the …, 2020 - cambridge.org
Sarcopenic obesity is characterised by the double burden of diminished skeletal muscle
mass and the presence of excess adiposity. From a mechanistic perspective, both obesity …
mass and the presence of excess adiposity. From a mechanistic perspective, both obesity …
The effects of age and muscle contraction on AMPK activity and heterotrimer composition
SE Hardman, DE Hall, AJ Cabrera, CR Hancock… - Experimental …, 2014 - Elsevier
Sarcopenia is characterized by increased skeletal muscle atrophy due in part to alterations
in muscle metabolism. AMP-activated protein kinase (AMPK) is a master regulator of skeletal …
in muscle metabolism. AMP-activated protein kinase (AMPK) is a master regulator of skeletal …