Parkinson disease (PD) is a progressive disorder characterized by dopaminergic
neurodegeneration in the brain. The development of parkinsonism is preceded by a long …

Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …

INTRODUCTION White matter in the human brain serves a critical role in organizing
distributed neural networks. Diffusion magnetic resonance imaging (dMRI) has enabled the …

Abstract Complex I (NADH dehydrogenase, NDU) and complex IV (cytochrome-c-oxidase,
COX) of the mitochondrial electron transport chain have been implicated in the …

Parkinson's disease involves multiple neurotransmitter systems beyond the classical
dopaminergic circuit, but their influence on structural and functional alterations is not well …

The incidence of neurodegenerative diseases has shown an increasing trend. These
conditions typically cause progressive functional disability. Identification of robust …

The human brain forms functional networks of correlated activity, which have been linked
with both cognitive and clinical outcomes. However, the genetic variants affecting brain …

Parkinson's disease (PD) is a movement disorder characterized by the early loss of
nigrostriatal dopaminergic pathways producing significant network changes impacting motor …

There has been an increasing prevalence of neurodegenerative diseases with the rapid
increase in aging societies worldwide. Biomarkers that can be used to detect pathological …

Progressive Supranuclear Palsy (PSP) and Parkinson's Disease (PD), especially in their
early stages, show overlapping clinical manifestations. The criteria for the diagnosis of PSP …