Destructive effects of hepatocellular carcinoma (HCC) is enhanced by many cellular
mechanisms including activation of fibrosis, inflammation and tumor invasion. Therefore, this …

Systemic treatment for advanced hepatocellular carcinoma (HCC) has been revolutionized
over the last few years following the approval of immune checkpoint inhibitors (ICI). Despite …

Gelsemium elegans (G. elegans) Benth., recognized as a toxic plant, has been used as
traditional Chinese medicine for the treatment of neuropathic pain and cancer for many …

Hepatocellular carcinoma (HCC) is one of the most aggressive and truculent types of
cancer. Early detection of HCC is a massive concern that can boost the overall survival rates …

Hepatocellular carcinoma (HCC) represents a major and steadily increasing global health
challenge as the most common primary liver malignancy and leading cause of death in …

Background: Hepatocellular Carcinoma (HCC) is a primary liver cancer with high mortality.
Paeoniflorin is a pinane monoterpene picroside with anti-tumor effect isolated from Chinese …

Chronic liver disease (CLD) is considered the leading cause of global mortality. In
westernized countries, increased consumption of alcohol and overeating foods with high …

Upregulated ubiquitin-conjugating enzyme E2M (UBE2M) is associated with poor prognosis
in malignancies; However, the phenotype and mechanism of action of UBE2M in …

Aurora A kinase (AURKA) is an important regulator in mitotic progression and is
overexpressed frequently in human cancers, including hepatocellular carcinoma (HCC) …

Epithelial-mesenchymal transition (EMT) occurs in the progression of liver fibrosis, cirrhosis,
and hepatocellular carcinoma (HCC). The hydroxysteroid sulfotransferase 2B1b …