[HTML][HTML] Target therapy for hepatocellular carcinoma: Beyond receptor tyrosine kinase inhibitors and immune checkpoint inhibitors

H Park, H Park, J Baek, H Moon, SW Ro - Biology, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is the most common type of primary liver
cancer and its incidence is steadily increasing. The development of HCC is a complex, multi …

[HTML][HTML] PBMCs gene expression signature of advanced cirrhosis with high risk for clinically significant portal hypertension in HIV/HCV coinfected patients: A cross …

S Salgüero, Ó Brochado-Kith, AV Verdices… - Biomedicine & …, 2023 - Elsevier
Background Patients with advanced cirrhosis are at high risk of developing clinically
significant portal hypertension (CSPH). We analyzed the gene expression profile of …

[HTML][HTML] Evaluating the Potential Anticancer Properties of Salvia triloba in Human-Osteosarcoma U2OS Cell Line and Ovarian Adenocarcinoma SKOV3 Cell Line

NAM Saleh, RBEA El-bary, EZ Mpingirika, HL Essa… - Applied Sciences, 2022 - mdpi.com
Salvia triloba (S. triloba) is an herb inherently linked to traditional medicine systems in the
Eastern Mediterranean region. There is minimal experimental evidence however, regarding …

[PDF][PDF] Mechanisms and clinical behavior of hepatocellular carcinoma in HBV and HCV infection and alcoholic and non-alcoholic fatty liver disease

R Nevola, L Rinaldi, M Giordano, A Marrone… - Hepatoma …, 2018 - academia.edu
Hepatocellular carcinoma (HCC) is the main tumor of the liver and is the sixth most
frequently diagnosed tumor in the world. It is the evolution of chronic hepatic injury …

[HTML][HTML] Custom gene expression panel for evaluation of potential molecular markers in hepatocellular carcinoma

SR Pallerla, NX Hoan, S Rachakonda, CG Meyer… - BMC Medical …, 2022 - Springer
Background Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related
mortality worldwide. It is a highly heterogeneous disease with poor prognosis and limited …

[HTML][HTML] Role of genetic and epigenetic modifications in the progression of hepatocellular carcinoma in chronic HCV patients

A Syyam, HR Akbar, ZM Jilkova, S Afzal - Livers, 2023 - mdpi.com
Globally, hepatocellular carcinoma (HCC) is a significant cause of mortality and morbidity
among chronically infected HCV patients. It is established that HCV is a primary risk factor …

[HTML][HTML] Key oncogenic signaling pathways affecting tumor-infiltrating lymphocytes infiltration in hepatocellular carcinoma: basic principles and recent advances

X Wang, Z Yuan, Z Li, X He, Y Zhang, X Wang… - Frontiers in …, 2024 - frontiersin.org
The incidence of hepatocellular carcinoma (HCC) ranks first among primary liver cancers,
and its mortality rate exhibits a consistent annual increase. The treatment of HCC has …

[HTML][HTML] Role of methylated septin 9 as an adjunct diagnostic and prognostic biomarker in hepatocellular carcinoma

AS Bannaga, R Alvarez, L Zhou, M Petchey, A Noufaily… - HPB, 2021 - Elsevier
Abstract Background Methylated septin 9 (mSEPT9) has a role in hepatocarcinogenesis. We
evaluated mSEPT9 performance in patients with hepatocellular carcinoma (HCC) and those …

Salinomycin induces cell cycle arrest and apoptosis and modulates hepatic cytochrome P450 mRNA expression in HepG2/C3a cells

AM Niwa, SC Semprebon, GFR D'Epiro… - Toxicology …, 2022 - Taylor & Francis
Salinomycin (SAL) is a monocarboxylic polyether ionophore antibiotic isolated from
Streptomyces albus. It exhibits an effective antitumor potential against numerous human …

QNZ alleviated hepatocellular carcinoma by targeting inflammatory pathways in a rat model

MMH Al-Gayyar, A Alattar, R Alshaman, AM Hamdan - Cytokine, 2021 - Elsevier
The pathogenicity of HCC could be enhanced by TNF-α and NFκB, which are crucial parts of
the inflammatory pathway inside the HCC microenvironment. Therefore, we aimed to …