Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis

M Tan, Y Yin, X Ma, J Zhang, W Pan, M Tan… - Cell Death & …, 2023 - nature.com
The glutathione (GSH) system is considered to be one of the most powerful endogenous
antioxidant systems in the cardiovascular system due to its key contribution to detoxifying …

Chlorogenic acids in cardiovascular disease: A review of dietary consumption, pharmacology, and pharmacokinetics

L Li, C Su, X Chen, Q Wang, W Jiao… - Journal of agricultural …, 2020 - ACS Publications
Chlorogenic acids (CGAs) have gained considerable attention as pervasive human dietary
constituents with potential cardiovascular-preserving effects. The main sources include …

A review of the protective effects of chlorogenic acid against different chemicals

R Rashidi, R Rezaee, A Shakeri… - Journal of Food …, 2022 - Wiley Online Library
Chlorogenic acid (CGA) is a naturally occurring non‐flavonoid polyphenol found in green
coffee beans, teas, certain fruits, and vegetables, that exerts antiviral, antitumor …

Molecular understanding of the protective role of natural products on isoproterenol-induced myocardial infarction: A review

ZW Wong, PV Thanikachalam… - Biomedicine & …, 2017 - Elsevier
Modern medicine has been used to treat myocardial infarction, a subset of cardiovascular
diseases, and have been relatively effective but not without adverse effects. Consequently …

Momordica charantia polysaccharides ameliorate oxidative stress, hyperlipidemia, inflammation, and apoptosis during myocardial infarction by inhibiting the NF-κB …

M Raish - International journal of biological macromolecules, 2017 - Elsevier
The polysaccharide extract of Momordica charantia has various biological activities;
however, its effect on endothelial dysfunction in myocardial infarction remains unclear. To …

Chlorogenic acid alleviates colon mucosal damage induced by a high‐fat diet via gut microflora adjustment to increase short‐chain fatty acid accumulation in rats

MG Xie, YQ Fei, Y Wang, WY Wang… - Oxidative Medicine and …, 2021 - Wiley Online Library
A high‐fat diet (HFD) has been previously associated with the development of diseases
such as chronic colitis. While chlorogenic acid (CGA) is known to exhibit potent antioxidant …

Chlorogenic acid attenuates doxorubicin-induced oxidative stress and markers of apoptosis in cardiomyocytes via Nrf2/HO-1 and dityrosine signaling

B Cicek, A Hacimuftuoglu, Y Yeni, B Danisman… - Journal of Personalized …, 2023 - mdpi.com
(1) Background: Doxorubicin (DOX) is extensively used for cancer treatments; however, its
clinical application is limited because of its cardiotoxic adverse effects. A combination of …

[HTML][HTML] Chlorogenic acid prevents acute myocardial infarction in rats by reducing inflammatory damage and oxidative stress

D Wang, L Tian, H Lv, Z Pang, D Li, Z Yao… - Biomedicine & …, 2020 - Elsevier
Recent studies have suggested that the prevention of myocardial infarction (MI) through diet
is very important and that the intake of polyphenol-rich foods can improve cardiovascular …

Cardioprotective effect of the polysaccharide from Ophiopogon japonicus on isoproterenol-induced myocardial ischemia in rats

S Fan, J Zhang, Q Xiao, P Liu, Y Zhang, E Yao… - International journal of …, 2020 - Elsevier
Abstract The polysaccharide (OJP1), extracted from the root of Ophiopogon japonicus, is a
well-known traditional Chinese medicine used to treat cardiovascular diseases. The present …

The role of polyphenol in modulating associated genes in diabetes-induced vascular disorders

NA Mohd Nor, SB Budin, S Zainalabidin, J Jalil… - International Journal of …, 2022 - mdpi.com
Diabetes-induced vascular disorder is considered one of the deadly risk factors among
diabetic patients that are caused by persistent hyperglycemia that eventually leads to …