Chlamydia trachomatis Persistence In Vitro: An Overview

PB Wyrick - The Journal of infectious diseases, 2010 - academic.oup.com
Chlamydiae growing in target mucosal human epithelial cells in vitro can transition from their
normal developmental cycle progression, alternating between infectious but metabolically …

[HTML][HTML] The role of the immune response in Chlamydia trachomatis infection of the male genital tract: a double-edged sword

KA Redgrove, EA McLaughlin - Frontiers in immunology, 2014 - frontiersin.org
Chlamydia trachomatis (CT) is the most prevalent bacterial sexually transmitted infection in
the world, with more than 100 million cases reported annually. While there have been …

Bacterial moonlighting proteins and bacterial virulence

B Henderson, A Martin - Between pathogenicity and commensalism, 2011 - Springer
Implicit in the central dogma is the hypothesis that each protein gene product has but one
function. However, over the past decade, it has become clear that many proteins have one …

Chaperonin 60: a paradoxical, evolutionarily conserved protein family with multiple moonlighting functions

B Henderson, MA Fares, PA Lund - Biological Reviews, 2013 - Wiley Online Library
Chaperonin 60 is the prototypic molecular chaperone, an essential protein in eukaryotes
and prokaryotes, whose sequence conservation provides an excellent basis for …

[HTML][HTML] Persistence of obligate intracellular pathogens: alternative strategies to overcome host-specific stresses

CM Riffaud, EA Rucks, SP Ouellette - Frontiers in Cellular and …, 2023 - frontiersin.org
In adapting to the intracellular niche, obligate intracellular bacteria usually undergo a
reduction of genome size by eliminating genes not needed for intracellular survival. These …

[HTML][HTML] Timely approaches to identify probiotic species of the genus Lactobacillus

SR Herbel, W Vahjen, LH Wieler, S Guenther - Gut Pathogens, 2013 - Springer
Over the past decades the use of probiotics in food has increased largely due to the
manufacturer's interest in placing “healthy” food on the market based on the consumer's …

Chlamydia trachomatis, a Hidden Epidemic: Effects on Female Reproduction and Options for Treatment

AJ Carey, KW Beagley - American journal of reproductive …, 2010 - Wiley Online Library
Citation Carey AJ, Beagley KW. Chlamydia trachomatis, a hidden epidemic: effects on the
female reproduction and options for treatment. Am J Reprod Immunol 2010 The number of …

[HTML][HTML] Chlamydia trachomatis infection: host immune responses and potential vaccines

L Hafner, K Beagley, P Timms - Mucosal immunology, 2008 - Elsevier
Chlamydia trachomatis causes genital tract infections that affect men, women, and children
on a global scale. This review focuses on innate and adaptive immune responses in the …

[HTML][HTML] Ironing Out the Unconventional Mechanisms of Iron Acquisition and Gene Regulation in Chlamydia

ND Pokorzynski, CC Thompson… - Frontiers in cellular and …, 2017 - frontiersin.org
The obligate intracellular pathogen Chlamydia trachomatis, along with its close species
relatives, is known to be strictly dependent upon the availability of iron. Deprivation of iron in …

Genomewide transcriptional responses of iron-starved Chlamydia trachomatis reveal prioritization of metabolic precursor synthesis over protein translation

AJ Brinkworth, MR Wildung, RA Carabeo - Msystems, 2018 - Am Soc Microbiol
Iron is essential for growth and development of Chlamydia. Its long-term starvation in
cultured mammalian cells leads to production of aberrant noninfectious chlamydial forms …