Cellular senescence: the good, the bad and the unknown

W Huang, LTJ Hickson, A Eirin, JL Kirkland… - Nature Reviews …, 2022 - nature.com
Cellular senescence is a ubiquitous process with roles in tissue remodelling, including
wound repair and embryogenesis. However, prolonged senescence can be maladaptive …

Chronic kidney disease

K Kalantar-Zadeh, TH Jafar, D Nitsch, BL Neuen… - The lancet, 2021 - thelancet.com
Chronic kidney disease is a progressive disease with no cure and high morbidity and
mortality that occurs commonly in the general adult population, especially in people with …

Targeting innate immunity-driven inflammation in CKD and cardiovascular disease

T Speer, S Dimmeler, SJ Schunk, D Fliser… - Nature Reviews …, 2022 - nature.com
Mortality among patients with chronic kidney disease (CKD) is largely a consequence of
cardiovascular disease (CVD) and is a particular concern given the increasing prevalence of …

Association of metabolic dysfunction-associated fatty liver disease with kidney disease

TY Wang, RF Wang, ZY Bu, G Targher… - Nature Reviews …, 2022 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is characterized by the accumulation of fat in more
than 5% of hepatocytes in the absence of excessive alcohol consumption and other …

[HTML][HTML] Ageing–oxidative stress, PTMs and disease

T Ebert, N Tran, L Schurgers, P Stenvinkel… - Molecular aspects of …, 2022 - Elsevier
Post-translational modifications (PTMs) have been proposed as a link between the oxidative
stress-inflammation-ageing trinity, thereby affecting several hallmarks of ageing …

Foodomics: Analytical opportunities and challenges

A Valdés, G Alvarez-Rivera… - Analytical …, 2021 - ACS Publications
Food analysis has traditionally been an important field of application of analytical chemistry.
Indeed, administrations, governments, consumers, and researchers worldwide rely on …

Inflammation and oxidative stress in chronic kidney disease and dialysis patients

T Ebert, O Neytchev, A Witasp… - Antioxidants & Redox …, 2021 - liebertpub.com
Significance: Chronic kidney disease (CKD) can be regarded as a burden of lifestyle
disease that shares common underpinning features and risk factors with the aging process; …

[HTML][HTML] An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease

DQ Sun, G Targher, CD Byrne… - … surgery and nutrition, 2023 - ncbi.nlm.nih.gov
Background With the rising global prevalence of fatty liver disease related to metabolic
dysfunction, the association of this common liver condition with chronic kidney disease …

Diet-derived antioxidants and their role in inflammation, obesity and gut microbiota modulation

A Deledda, G Annunziata, GC Tenore, V Palmas… - Antioxidants, 2021 - mdpi.com
It is generally accepted that gut microbiota, inflammation and obesity are linked to the
development of cardiovascular diseases and other chronic/non-communicable pathological …

The intestinal microbiota and metabolites in the gut-kidney-heart axis of chronic kidney disease

Y Huang, W Xin, J Xiong, M Yao, B Zhang… - Frontiers in …, 2022 - frontiersin.org
Emerging evidences demonstrate the involvement of gut microbiota in the progression of
chronic kidney disease (CKD) and CKD-associated complications including cardiovascular …