[HTML][HTML] Recent progress regarding kaempferol for the treatment of various diseases

JIE Ren, Y Lu, Y Qian, B Chen… - Experimental …, 2019 - … .spandidos-publications.com
Kaempferol, also known as kaempferol‑3 or kaempferide, is a flavonoid compound that
naturally occurs in tea, as well as numerous common vegetables and fruits, including beans …

[HTML][HTML] Chemopreventive and anticancer activity of flavonoids and its possibility for clinical use by combining with conventional chemotherapeutic agents

H Kikuchi, B Yuan, X Hu, M Okazaki - American journal of cancer …, 2019 - ncbi.nlm.nih.gov
Cancer is a diverse class of diseases characterized by uncontrolled cell growth with the
potential to invade and spread to other parts of the body, and continues to be one of the …

Kaempferol induces ROS-dependent apoptosis in pancreatic cancer cells via TGM2-mediated Akt/mTOR signaling

F Wang, L Wang, C Qu, L Chen, Y Geng, C Cheng… - BMC cancer, 2021 - Springer
Background Kaempferol, a natural flavonoid, exhibits anticancer properties by scavenging
reactive oxygen species (ROS). However, increasing evidence has demonstrated that …

Rumex vesicarius L. boosts the effectiveness of sorafenib in triple-negative breast cancer by downregulating BCl2, mTOR, and JNK, and upregulating p21 expression

A Ghanem, MA Ali, MA Elkady, SSA Mageed… - … -Research and Practice, 2023 - Elsevier
Abstract Background/Aim Triple-negative breast cancer (TNBC) is characterized by poor
prognosis, rapid progression, serious clinical behavior, an elevated risk of metastasis, and …

Therapeutic importance of kaempferol in the treatment of cancer through the modulation of cell signalling pathways

MY Qattan, MI Khan, SH Alharbi, AK Verma… - Molecules, 2022 - mdpi.com
Plant-derived flavonoids are considered natural nontoxic chemo-preventers and have been
widely studied for cancer treatment in recent decades. Mostly all flavonoid compounds show …

Flavonoids: A myth or a reality for cancer therapy?

C Forni, M Rossi, I Borromeo, G Feriotto, G Platamone… - Molecules, 2021 - mdpi.com
Nutraceuticals are biologically active molecules present in foods; they can have beneficial
effects on health, but they are not available in large enough quantities to perform this …

Targeting PI3K/Akt/mTOR signaling pathway by polyphenols: Implication for cancer therapy

M Mirza-Aghazadeh-Attari, EM Ekrami, SAM Aghdas… - Life sciences, 2020 - Elsevier
Cancer is one of the biggest challenges facing medicine and its cure is regarded to be the
Holy Grail of medicine. Therapy in cancer is consisted as various artificial cytotoxic agents …

Kaempferol and atherosclerosis: From mechanism to medicine

M Chen, J Xiao, HR El-Seedi, KS Woźniak… - Critical Reviews in …, 2024 - Taylor & Francis
Natural products possess pleiotropic cardiovascular protective effects owing to their anti-
oxidation, anti-inflammation and anti-thrombotic properties. Kaempferol,(3, 5, 7-trihydroxy-2 …

Current understanding of flavonoids in cancer therapy and prevention

M Farhan, A Rizvi, M Aatif, A Ahmad - Metabolites, 2023 - mdpi.com
Cancer is a major cause of death worldwide, with multiple pathophysiological
manifestations. In particular, genetic abnormalities, inflammation, bad eating habits …

Targeting cancer with phytochemicals via their fine tuning of the cell survival signaling pathways

S Chirumbolo, G Bjørklund, R Lysiuk, A Vella… - International journal of …, 2018 - mdpi.com
The role of phytochemicals as potential prodrugs or therapeutic substances against tumors
has come in the spotlight in the very recent years, thanks to the huge mass of encouraging …